Results 41 to 50 of about 109,876 (305)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

NESTS

open access: yes, 2015
NEST
Bowers, E. Keith   +5 more
core   +2 more sources

Nested melanoma

open access: yesDermatology Reports, 2021
This case was presented at the on-line meeting on the ADOI platform held on October 27th 2021 by Dr Zardo.
Davide Zardo   +2 more
openaire   +3 more sources

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Reproductive indices in natural nests of giant Amazon river turtles Podocnemis expansa (Schweigger, 1812) (Testudines, Podocnemididae) in the Environmental Protection Area Meanders of the Araguaia river

open access: yesBrazilian Journal of Biology
A count was made of unhatched eggs and hatchling live and dead Podocnemis expansa turtles in 327 natural nests located on the beaches of the Environmental Protection Area (EPA) Meanders of the Araguaia River, to determine the percentage of hatching (94 ...
JRF Alves-Júnior   +6 more
doaj   +1 more source

Effect of Feathers as Nest Insulation on Incubation Behavior and Reproductive Performance of Tree Swallows (\u3cem\u3eTachycineta bicolor\u3c/em\u3e) [PDF]

open access: yes, 1995
Many species of birds line their nests with feathers, presumably because of the insulative qualities of feathers and because feathers may act as a barrier between nest parasites and nestlings.
Faro, Christine A   +4 more
core  

Plastic found lining UK seabird nests on a worrying scale [PDF]

open access: yes, 2020
First paragraph: From the packaging our food comes in to the clothes we wear, plastic is everywhere. We know that seabirds eat it and get tangled in it, but we are only just beginning to explore the impacts this has on their health and survival.
Ovenden, Tom
core  

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

The occurrence and distribution of cellulolytic fungi and Fusarium in seven Montagu’s Harrier (Circus pygargus)

open access: yesActa Mycologica, 2013
A total of 45 species of cellulolytic fungi and ten Fusarium species were identified. Three genera (Chaetomium, Trichoderma, Fusarium) represented 80% of the frequency of cellulolytic fungi.
Teresa Korniłłowicz-Kowalska   +2 more
doaj   +1 more source

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