Results 61 to 70 of about 559,862 (302)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Regional Distribution of Net Radiation over Different Ecohydrological Land Surfaces

Atmosphere, 2020
Net radiation is an important component of the earth’s surface energy balance, which plays a vital role in the evolution of regional climate or climate change.
Md Masudur Rahman, Wanchang Zhang, Arfan Arshad   +2 more
doaj   +1 more source

Nonequilibrium ionization states and cooling rates of the photoionized enriched gas [PDF]

, 2006
Nonequilibrium (time-dependent) cooling rates and ionization state calculations are presented for low-density gas enriched with heavy elements (metals) and photoionized by external ultraviolet/X-ray radiation.
Au-Yang, Baxter, Behrend, Gaudin, Kennelly, Korepin, Kulish, Lieb, Onsager, Perk, Perk, Perk, Reidemeister, Reidemeister, Yang, Yang   +15 more
core   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Modelagem Simplificada Para Estimativa do Balanço de Energia à Superfície em Escala Regional (R-SSEB)

Revista Brasileira de Meteorologia
Resumo Este estudo apresenta uma metodologia simplificada e ajustada a partir de algoritmos existentes a dados de sensores orbitais disponíveis para a região Nordeste do Brasil (NEB) com o intuito de operacionalizar a determinação espacial da ...
Argemiro Lucena de Araújo, Madson Tavares Silva, Bernardo Barbosa da Silva, Carlos Antonio Costa dos Santos, Marcos Renato Basílio do Amorim   +4 more
doaj   +1 more source

A possible use for polarizers in imaging atmospheric Cherenkov telescopes [PDF]

, 2001
Cherenkov radiation produced in Extensive Air Showers shows a net polarization. This article discusses its properties and physical origin, and proposes an arrangement of polarizers potentially useful for Imaging Atmospheric Cherenkov Telescopes.Comment ...
Cherenkov Telescopes, I. De La Callea, J. Cortinac, J. L. Contrerasb, V. Fonsecab   +4 more
core   +3 more sources

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Avaliação dos componentes do balanço de energia durante o primeiro ano de cultura da banana Evaluation of components of energy balance in banana crop during the first year

Revista Brasileira de Engenharia Agrícola e Ambiental, 2001
Dados de saldo de radiação, fluxo de calor no solo, gradientes de temperatura e pressão do vapor, coletados no Campo Experimental da Embrapa Semi-Árido, em Petrolina, PE, foram utilizados na avaliação dos comportamentos diurno e sazonal dos componentes ...
Antônio H. de C. Teixeira
doaj   +1 more source

The Variability of the Net Radiation Ratio [PDF]

Hydrology Research, 1976
Prediction equations for estimating evaporation from bodies of water, often require values of net radiation. Solar radiation data are usually more accurate and more readily available than measurements of net radiation. Measured solar radiation and the mean ratio of net radiation to solar radiation have been used to estimate the net radiation levels ...
Loris E. Asmussen, Richard H. Mc Cuen
openaire   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source