Results 1 to 10 of about 1,032 (108)

Oral and parenteral vaccination of broiler chickens with Recombinant NetB antigen from Clostridium perfringens confers significant protection against necrotic enteritis [PDF]

BMC Veterinary Research
Background Necrotic enteritis is a devastating economic disease caused by Clostridium perfringens in poultry. NetB toxin from C. perfringens type G is the major responsible cause of necrotic enteritis.
Mehdi Golchin, Mohammad Ali Shamshirgaran   +1 more
exaly   +3 more sources

Molecular detection and sequencing of the NetB toxin Gene of clostridium perfringens and evaluation of its pathogenicity in broiler chicken [PDF]

Poultry Science
Clostridium perfringens is the primary cause of necrotic enteritis (NE), one of the most economically destructive illnesses in broiler production. The virulence of this pathogen has recently been linked to the NetB toxin gene, a pore-producing cytotoxin ...
Ibrahim Eldaghayes, Ahmed Hassan
exaly   +4 more sources

An engineered Escherichia coli-ClyA-NetB outer membrane vesicle delivery system modulates jejunal microbiota in broiler chickens with necrotic enteritis. [PDF]

Poult Sci
Necrotic enteritis (NE), caused by Clostridium perfringens (CP), remains one of the most economically consequential enteric diseases in broiler production, and currently available preventive strategies provide incomplete protection.
Lin F, Wu CE, Yang WY.
europepmc   +2 more sources

Distribution of NetB toxin in chickens infected with Clostridium Perfringens and cytotoxicity study of NetB toxin. [PDF]

Poult Sci
Avian necrotic enteritis (NE) causes significant economic losses to the global poultry industry. Clostridium perfringens NetB toxin is a key virulence factor causing necrotizing enteritis in chickens, but the receptor of the toxin remains unknown, and ...
Kong XY, Song YN, Wang HR.
europepmc   +2 more sources

NetB, a New Toxin That Is Associated with Avian Necrotic Enteritis Caused by Clostridium perfringens [PDF]

PLoS Pathogens, 2008
For over 30 years a phospholipase C enzyme called alpha-toxin was thought to be the key virulence factor in necrotic enteritis caused by Clostridium perfringens.
Paola Vaz, Dane Parker, Robert J. Moore
exaly   +2 more sources

Identification of a Key Residue for Oligomerisation and Pore-Formation of Clostridium perfringens NetB

Toxins, 2014
Necrotic enteritis toxin B (NetB) is a β-pore-forming toxin produced by Clostridium perfringens and has been identified as a key virulence factor in the pathogenesis of avian necrotic enteritis, a disease causing significant economic damage to the ...
Richard W Titball, Monika Bokori-Brown, Christos G Savva   +2 more
exaly   +3 more sources

First genomic analysis of a <i>Clostridium perfringens</i> strain carrying both the <i>cpe</i> and <i>netB</i> genes and the proposal of an amended toxin-based typing scheme. [PDF]

Front Microbiol
Clostridium perfringens strains are classified into seven toxinotypes (A–G) based on the profiles of the six typing toxin genes. Among these toxins, NetB is known as an important virulence factor for necrotic enteritis in chickens, and its gene, netB, is
Mada T, Ochi K, Okamoto M, Takamatsu D.
europepmc   +2 more sources

NetB, a Pore-Forming Toxin from Necrotic Enteritis Strains of Clostridium perfringens

Toxins, 2010
The Clostridium perfringens necrotic enteritis B-like toxin (NetB) is a recently discovered member of the β-barrel pore-forming toxin family and is produced by a subset of avian C. perfringens type A strains.
Robert J. Moore, Julian I. Rood, Trudi L Bannam   +2 more
exaly   +3 more sources

Organoids as a model system for researching human neuroendocrine tumor of the breast. [PDF]

Cancer Cell Int
Background Neuroendocrine tumors primarily consist of endocrine cells commonly located in neural tissue and the endocrine system. Primary neuroendocrine neoplasms of the breast are highly heterogeneous tumors characterized by a diverse cell population ...
Zhao D, Bai X, Zhu S, Zhao Z, Li X.
europepmc   +2 more sources

Molecular epidemiology and PFGE-based genetic diversity of Clostridium perfringens in broiler chickens from Eastern Türkiye. [PDF]

BMC Vet Res
Background Clostridium perfringens is a ubiquitous foodborne and opportunistic anaerobe and a leading cause of necrotic enteritis (NE) in broiler chickens, with implications for animal health, food safety, and public health.
Karagulle B, Yerlikaya Z, Muz A.
europepmc   +2 more sources