Results 41 to 50 of about 3,353,954 (329)

Impacts of School Organization and Signaling on Incentives to Learn in France, the Netherlands, England, Scotland and the United States [PDF]

open access: yes, 1993
[Excerpt] Despite similar cultural roots and standards of living, the secondary education systems of France, the Netherlands, England, Scotland and the United States produce remarkably different levels of achievement in mathematics and science.
Bishop, John H.
core   +1 more source

The Netherlands [PDF]

open access: yes, 2021
The Netherlands’ constitutional system is based mainly on the Constitution (Grondwet), which dates back to 1814, but was revised many times. The latest major revision was in 1983 when the entire text and structure of the document were modernised, and a catalogue of fundamental rights was inserted as Chapter I.
Reestman, J.-H., Claes, M.
openaire   +4 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Kingdom of the Netherlands-Netherlands: Selected Issues [PDF]

open access: yesIMF Staff Country Reports, 2002
Overall competitiveness of the Dutch economy seems adequate, but domestically produced exports have lost market share recently. Over the past three decades, globalization has greatly influenced economies as countries have become more integrated. Empirical studies on business cycles synchronization and transmission of shocks among countries have ...
openaire   +6 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Emigration of the Dutch and their search of the "good life" [PDF]

open access: yes, 2008
For the first time since the 1950s the Netherlands is experiencing an emigration wave. A large-scale survey on the determinants of emigration has shown that most Dutch emigrants are in search of the good life: space, nature, peace and quiet and friendly ...
Dalen van, H.P.   +2 more
core   +1 more source

The Chinese From Indonesia in the Netherlands and Their Heritage Chinese Indonesian Heritage Center (CIHC) [PDF]

open access: yes, 2017
Chinese from Indonesia in the Netherlands are (post)colonial migrants who share a long historical tie with the Dutch. In this article the author brings together and focuses on three interconnected subjects: Chinese from Indonesia in the Netherlands; the ...
Liem, P. T. (Patricia)
core   +3 more sources

The influence of ROS1 fusion partners and resistance mechanisms in ROS1‐TKI‐treated non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
This real‐world study of ROS1+ NSCLC highlights fusion diversity, treatment outcomes with crizotinib and lorlatinib, and in vitro experiments with resistance mechanisms. G2032R drives strong resistance to ROS1‐targeted TKIs, especially lorlatinib. Fusion partner location does not affect overall survival to crizotinib or lorlatinib. Findings support the
Fenneke Zwierenga   +8 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

The organic market in the Netherlands [PDF]

open access: yes, 2011
The organic sector in the Netherlands is varied and vibrant. To be able to adequately respond to market trens, opportunities and threats, farmers and their partners in the production chains need high quality information about consumption and trends.
Meeusen, Marieke
core  

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