Results 41 to 50 of about 3,719,549 (330)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Journal of Long-Term Care, 2019 Context: Throughout Europe, the financial risks of health and long-term care are covered to varying degrees through models of national (health) insurance. Such insurance draws upon the principle of solidarity. Much is unknown on the solidarity-effects of
Maartje J. van der Aa +4 more
doaj +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Responsive corporatism without political credit: social concertation, constructive opposition and the long tenure of the Rutte II cabinet in the Netherlands (2012–2017) [PDF]
, 2022 Anton Hemerijck +2 more
openalex +1 more source
Impacts of School Organization and Signaling on Incentives to Learn in France, the Netherlands, England, Scotland and the United States [PDF]
, 1993 [Excerpt] Despite similar cultural roots and standards of living, the secondary education systems of France, the Netherlands, England, Scotland and the United States produce remarkably different levels of achievement in mathematics and science.
Bishop, John H.
core +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
The organic market in the Netherlands [PDF]
, 2011 The organic sector in the Netherlands is varied and vibrant. To be able to adequately respond to market trens, opportunities and threats, farmers and their partners in the production chains need high quality information about consumption and trends.
Meeusen, Marieke
core
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Atebe, 2022 Bu çalışmada Hollanda’da, İslam Araştırmaları alanında son yirmi küsur yılda üretilmiş olan akademik müktesebat ele alınmıştır. Makalede Hollanda’da İslam Araştırmaları alanında faaliyet gösteren Netherlands Interuniversity School for Islamic Studies ...
Murat Kayalık
doaj +1 more source
Molecular Oncology, EarlyView.Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard +12 more
wiley +1 more source