Results 81 to 90 of about 2,106,515 (290)
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Background HIV self-testing (HIVST) has the potential to increase testing uptake among populations underserved by facility/clinic-based services, including African migrants in Europe.
Oladipupo Shobowale +2 more
doaj +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Kingdom of the Netherlands—Netherlands
This 2014 Article IV Consultation highlights that the Dutch economy continues to improve, supported by exports, rising housing prices, and improving sentiment. Exports are rising on expanding global trade, but consumption remains sluggish as indebted households continue to save. The external current account surplus now exceeds 10 percent of GDP, led by
openaire +3 more sources
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Bijgewerkt ... [1962]Depths shown by bathymetric isolines, bathymetric tints and soundings.; Map in 2 segments.; Date derieved from purple stamp.; Includes notes, conversion table and 1 inset map: [Dordrecht]; Annotations in pencil.; Selected lights ...
Netherlands. Hydrografisch Bureau;
core
Special Education Systems in Five Countries: Indonesia, Norway, Malaysia, Netherlands, Thailand
This article discusses a comparison of special education in five countries. Two countries are on the continent of Europe, and three other countries are on Asia's continent. This article describes the forms of special education that exist in each country.
Dewi Kurniati, Herry Widyastono
doaj
The Dutch embraced in the 1920s the idea that they could improve society by forcing antisocial families in so-called housing schools. Slums were cleared under the pre-text of urban renewal, and vulnerable families were put under supervision in special ...
Frank van der Hoeven
doaj +1 more source
Formation of milk prices in Ukraine in the context of world trends
Purpose. The purpose of this article is to assess trends in milk prices in Ukraine in comparison with other countries, identify patterns in their change and to test our own methodological approach to estimating the level of variation in time series ...
Natalia Shyian, Valerii Kolosha
doaj +1 more source
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source

