Results 71 to 80 of about 5,369,575 (284)
Frontiers in Aging NeuroscienceBackgroundCognitive impairment (CI) is common in Parkinson’s disease (PD). Multiple brain regions and their interactions are involved in PD associated CI.
Rong-Pei Liu +10 more
doaj +1 more source
Repenser les liens entre l’histoire de l’art et la nation
Perspective, 2018 Initiating a fruitful dialogue within the idea of nation and the linguistic constellation that surrounds it, the works of Éric Michaud and Michela Passini question the role of art history in the constructions of identity.
Maddalena Carli
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Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Network Hybrid Form of the Kedem–Katchalsky Equations for Non-homogenous Binary Non-electrolyte Solutions: Evaluation of $$P_{ij}^{*}$$ P i j ∗ Peusner’s Tensor Coefficients [PDF]
, 2014 Kornelia Batko +2 more
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Networks, NetWorks, NETWorks, NETWORKS
, 1997 Business networks are having different characteristics and building blocs when looked upon from diverse perspectives. In this paper the aim is to highlight some aspects of the multi-facetted nature of business networks in marketing between industrial companies especially. A model is used as a base for discussing different networks in business settings.
openaire +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source