Results 81 to 90 of about 13,666,649 (339)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Debt Reduction for Poverty Eradication in the Least Developed Countries: Analysis and Recommendations on LDC Debt [PDF]
Debt , Poverty, Economic development, Foreign aid , Debt ...
European Network on Debt and Development
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Frontiers in PediatricsThe Pediatric Intensive Care Unit Admissions (PIA) network aims to establish a nationwide database in Germany to gather epidemiological, clinical, and outcome data on pediatric critical illness.
Nora Bruns +12 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Danse, mobilités et dynamiques territoriales au Mali
Géographie et Cultures, 2015 In Mali the music dance genre locally called ‘ballet’ mainly developed from the independence of the country (1960) through the creation of the state-sponsored National Ballet and private dance companies later on.
Élina Djebbari
doaj +1 more source
Percolation of hierarchical networks and networks of networks
Physical Review E, 2018 Much work has been devoted to studying percolation of networks and interdependent networks under varying levels of failures. Researchers have considered many different realistic network structures, but thus far no study has incorporated the hierarchical structure of many networks.
Shekhtman, Louis M., Havlin, Shlomo
openaire +3 more sources
Symposium on Revenue Transparency, Resource Development, and the Challenge of Corruption [PDF]
Revenue transparency and corruption in the mining industry have long been topics of national and international conversation. Mining plays an important role in the Canadian economy, contributing billions to Canada’s GDP.
Canadian Business Ethics Research Network (CBERN)
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