Results 141 to 150 of about 33,370,815 (408)

Network analysis of multivariate data in psychological science

open access: yesNature Reviews Methods Primers, 2021
D. Borsboom   +14 more
semanticscholar   +1 more source

Targeting PRAME directly or via EZH2 inhibition overcomes retinoid resistance and represents a novel therapy for keratinocyte carcinoma

open access: yesMolecular Oncology, EarlyView.
The study evaluated the function and therapeutic implications of PRAME in basal cell carcinoma (BCC) and squamous cell carcinoma (SCC). The findings demonstrate that PRAME impairs keratinocyte differentiation pathways. Furthermore, PRAME impairs anticancer response to retinoid compounds in BCC and SCC cells.
Brandon Ramchatesingh   +6 more
wiley   +1 more source

Clinical commissioning of an adaptive radiotherapy platform: Results and recommendations

open access: yesJournal of Applied Clinical Medical Physics, Volume 23, Issue 12, December 2022., 2022
Abstract Online adaptive radiotherapy platforms present a unique challenge for commissioning as guidance is lacking and specialized adaptive equipment, such as deformable phantoms, are rare. We designed a novel adaptive commissioning process consisting of end‐to‐end tests using standard clinical resources.
Kelly Kisling   +5 more
wiley   +1 more source

Isospectral Reductions of Dynamical Networks [PDF]

open access: yesarXiv, 2010
We present a general and flexible procedure which allows for the reduction (or expansion) of any dynamical network while preserving the spectrum of the network's adjacency matrix. Computationally, this process is simple and easily implemented for the analysis of any network. Moreover, it is possible to isospectrally reduce a network with respect to any
arxiv  

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

open access: yesMolecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song   +13 more
wiley   +1 more source

Network Inference in Public Administration: Questions, Challenges, and Models of Causality [PDF]

open access: yesarXiv
Descriptive and inferential social network analysis has become common in public administration studies of network governance and management. A large literature has developed in two broad categories: antecedents of network structure, and network effects and outcomes.
arxiv  

Measuring the Clustering Strength of a Network via the Normalized Clustering Coefficient [PDF]

open access: yesarXiv, 2019
In this paper, we propose a novel statistic of networks, the normalized clustering coefficient, which is a modified version of the clustering coefficient that is robust to network size, network density and degree heterogeneity under different network generative models.
arxiv  

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

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