Results 91 to 100 of about 426,398 (306)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Instantly Decodable Network Coding Protocols with Unequal Error Protection

, 2013
This work aims at introducing two novel packet retransmission techniques for reliable multicast in the framework of Instantly Decodable Network Coding (IDNC).
Matteo Berioli, Muhammad, Muhammad, Giovanni Giambene, Muhammad Muhammad, Berioli, Matteo, Liva, Gianluigi, Giambene, Giovanni, Gianluigi Liva   +7 more
core   +1 more source

A Geometric Framework for Investigating the Multiple Unicast Network Coding Conjecture [PDF]

, 2012
The multiple unicast network coding conjecture states that for multiple unicast sessions in an undirected network, network coding is equivalent to routing. Simple and intuitive as it appears, the conjecture has remained open since its proposal in 2004 [1]
Zongpeng Li, Li, Z, Chuan Wu, Huang, J, Xiahou, T, Jiaqing Huang, Wu, C, Tang Xiahou   +7 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Network coding via evolutionary algorithms [PDF]

Network coding (NC) is a relatively recent novel technique that generalises network operation beyond traditional store-and-forward routing, allowing intermediate nodes to combine independent data streams linearly.
Karunarathne, Lalith
core  

O2-GIDNC: Beyond instantly decodable network coding

, 2016
In this paper, we are concerned with extending the graph representation of generalized instantly decodable network coding (GIDNC) to a more general opportunistic network coding (ONC) scenario, referred to as order-2 GIDNC (O2-GIDNC).
Sorour, Sameh, Sadeghi, Parastoo, Aboutorab, Neda   +2 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Multiple Source Cooperation: From Code Division Multiplexing To Variable-Rate Network Coding

, 2011
Multiple-source cooperation techniques, including conventional code-division multiplexing (CDM) and classic network coding (CNC), are investigated. We adopt a soft sum - product decoding algorithm for the CNC technique to efficiently process a large ...
Rong Zhang, Zhang, Rong, Hanzo, Lajos, Lajos Hanzo   +3 more
core   +1 more source

POND: A Novel Protocol for Network Coding based on Hybrid Cryptographic Scheme [PDF]

, 2014
Network coding has been shown to have a lot of positive effects on networks. However, its mixing nature contributes to its vulnerability to pollution attacks.
Atsuko Miyaji, Longhai Li, Chengqiang Huang, Li, Long-Hai, Miyaji, Atsuko, Huang, Cheng-Qiang, Xu, Shang-Mei, Shangmei Xu   +7 more
core   +1 more source