Results 81 to 90 of about 414,943 (258)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Network Coding on Heterogeneous Multi-Core Processors for Wireless Sensor Networks

open access: yesSensors, 2011
While network coding is well known for its efficiency and usefulness in wireless sensor networks, the excessive costs associated with decoding computation and complexity still hinder its adoption into practical use.
Won W. Ro, Deokho Kim, Karam Park
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Quantum Network Coding [PDF]

open access: yes, 2007
Since quantum information is continuous, its handling is sometimes surprisingly harder than the classical counterpart. A typical example is cloning; making a copy of digital information is straightforward but it is not possible exactly for quantum information. The question in this paper is whether or not quantum network coding is possible.
Masahito Hayashi   +4 more
openaire   +6 more sources

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Entropy of Closure Operators and Network Coding Solvability

open access: yesEntropy, 2014
The entropy of a closure operator has been recently proposed for the study of network coding and secret sharing. In this paper, we study closure operators in relation to their entropy. We first introduce four different kinds of rank functions for a given
Maximilien Gadouleau
doaj   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

open access: yesMolecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both   +7 more
wiley   +1 more source

Genetic Algorithm-Based Cooperative Coding and Caching Data Dissemination Scheme in Multi-UAV-Enabled Internet of Vehicles

open access: yesSensors
Unmanned Aerial Vehicles (UAVs) have emerged as efficient tools in disaster-stricken areas, facilitating efficient data dissemination for post-disaster rescue operations.
Ke Xiao   +5 more
doaj   +1 more source

Cooperative Content Caching for Mobile Edge Computing With Network Coding

open access: yesIEEE Access, 2019
As an important technology in next-generation networks, mobile edge computing (MEC) can bring high-speed intelligent network services to users. However, planning MEC file transmission represents a problem to be urgently solved.
Weisheng He   +5 more
doaj   +1 more source

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