Results 61 to 70 of about 5,349,313 (285)
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Adversarial Network Coding [PDF]
A combinatorial framework for adversarial network coding is presented. Channels are described by specifying the possible actions that one or more (possibly coordinated) adversaries may take. Upper bounds on three notions of capacity (the one-shot capacity, the zero-error capacity, and the compound zero-error capacity) are obtained for point-to-point ...
Alberto Ravagnani, Frank R. Kschischang
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Near-Capacity Network Coding for Cooperative Multi-User Communications [PDF]
In this contribution, we investigate Near-Capacity Multiuser Network-coding (NCMN) based systems using an Irregular Convolutional Code, a Unity-Rate Code and M-ary Phase-Shift Keying.
Luiz Rebelatto, Joao +4 more
core +2 more sources
General Fractional Repetition Codes From Combinatorial Designs
Fractional repetition codes are a class of distributed storage codes dedicated to optimize the node repair performance, i.e., they enable uncoded exact repairs with minimum bandwidth consumption.
Bing Zhu, Hui Li, Shuo-Yen Robert Li
doaj +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
A Survey of Linear Network Coding and Network Error Correction Code Constructions and Algorithms
Network coding was introduced by Ahlswede et al. in a pioneering work in 2000. This paradigm encompasses coding and retransmission of messages at the intermediate nodes of the network.
Michele Sanna, Ebroul Izquierdo
doaj +1 more source
We consider communication over a noisy network under randomized linear network coding. Possible error mechanism include node- or link- failures, Byzantine behavior of nodes, or an over-estimate of the network min-cut. Building on the work of Koetter and Kschischang, we introduce a probabilistic model for errors.
Andrea Montanari, Rüdiger L. Urbanke
openaire +3 more sources

