Results 141 to 150 of about 1,267,357 (242)

Network design principle for robust oscillatory behaviors with respect to biological noise. [PDF]

Elife, 2022
Qiao L, Zhang ZB, Zhao W, Wei P, Zhang L.   +4 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

A mathematical modelling for integrated construction and production supply chain network design. [PDF]

Sci Rep
Helli SS, Mokhtari H, Dehnavi S.
europepmc   +1 more source

Automation of Macular Degeneration Classification in the AREDS Dataset, Using a Novel Neural Network Design. [PDF]

Clin Ophthalmol, 2023
Xie L, Vaghefi E, Yang S, Han D, Marshall J, Squirrell D.   +5 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Sustainable closed-loop supply chain network design under uncertainty using a fuzzy multi-objective optimization framework for the battery industry. [PDF]

Sci Rep
Attari MYN, Rezanejad S, Ala A, Simic V, Pamucar D.   +4 more
europepmc   +1 more source

Leveraging image complexity in macro-level neural network design for medical image segmentation. [PDF]

Sci Rep, 2022
Khan TM, Naqvi SS, Meijering E.
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Model-guided chemical environment and metabolic network design to couple pathways with cell fitness. [PDF]

Metab Eng Commun
Kakko von Koch N, Tenkanen T, Castillo S, Vidgren V, Koponen T, Krogerus K, Penttilä M, Jouhten P.   +7 more
europepmc   +1 more source

Impact of Mobile Monitoring Network Design on Air Pollution Exposure Assessment Models. [PDF]

Environ Sci Technol, 2023
Blanco MN, Bi J, Austin E, Larson TV, Marshall JD, Sheppard L.   +5 more
europepmc   +1 more source