Results 171 to 180 of about 4,643,840 (321)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Automation of Macular Degeneration Classification in the AREDS Dataset, Using a Novel Neural Network Design. [PDF]

Clin Ophthalmol, 2023
Xie L, Vaghefi E, Yang S, Han D, Marshall J, Squirrell D.   +5 more
europepmc   +1 more source

Design of an Energy-Efficient Ternary Current-Mode Intra-Chip Communication Link for an Asynchronous Network-on-Chip

, 2014
Akira Mochizuki, Hirokatsu Shirahama, Yuma Watanabe, Takahiro Hanyu   +3 more
openalex   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Network design principle for robust oscillatory behaviors with respect to biological noise. [PDF]

Elife, 2022
Qiao L, Zhang ZB, Zhao W, Wei P, Zhang L.   +4 more
europepmc   +1 more source

Design A CPW Fed Implantable Antenna at frequency 2.4 GHz for Wireless Implantable Body Area Network

, 2020
Nuraminah Ramli, H. Othman, Dayang Khadijah Hamzah   +2 more
openalex   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Matching Network Design for Ultrasonic Guided Wave Interdigital Transducers. [PDF]

Sensors (Basel)
Capineri L.
europepmc   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

A mathematical modelling for integrated construction and production supply chain network design. [PDF]

Sci Rep
Helli SS, Mokhtari H, Dehnavi S.
europepmc   +1 more source