Results 181 to 190 of about 21,554,636 (317)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

A mathematical modelling for integrated construction and production supply chain network design. [PDF]

Sci Rep
Helli SS, Mokhtari H, Dehnavi S.
europepmc   +1 more source

Modelling and Design of Inverter Threshold Quantization based Current Comparator using Artificial Neural Networks

, 2016
Veepsa Bhatia, Neeta Pandey, Asok Bhattacharyya   +2 more
openalex   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Network design for bypass roads using interval valued fuzzy outerplanar graphs. [PDF]

Sci Rep
Jaisankar D, Ramalingam S, Deivanayagampillai N, Walelign T.   +3 more
europepmc   +1 more source

Design And Implementation Of Medium Access Control Based Routing On Real Wireless Sensor Networks Testbed

, 2017
Smriti Agarwal, Ashish Payal, B. V. R. Reddy   +2 more
openalex   +1 more source

Edge caching strategy design and reward contract optimization for uAV-enabled mobile edge networks [PDF]

, 2020
Weidang Lu, Bin Yin, Guoxiang Huang, Bo Li   +3 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Baptism in a Pandemic: Infectious Diseases Clinical Research Consortium Network Design for Readiness and Response. [PDF]

Clin Infect Dis
Dionne JA, Campbell JD, Salim J, Atmar RL, Healy CM, Posavad CM, Flach B, Brown ER, Farley MM, Stephens DS.   +9 more
europepmc   +1 more source

The Optimal Cost Design of Reinforced Concrete Beams Using an Artificial Neural Network—The Effectiveness of Cost-Optimized Training Data [PDF]

Jeongmin So, Seungjae Lee, Ji-Young Seong, Donwoo Lee   +3 more
openalex   +1 more source