Results 131 to 140 of about 876,573 (316)

A Passenger Flow Control Method for Subway Network Based on Network Controllability

Discrete Dynamics in Nature and Society, 2018
The volume of passenger flow in urban rail transit network operation continues to increase. Effective measures of passenger flow control can greatly alleviate the pressure of transportation and ensure the safe operation of urban rail transit systems. The
Lu Zeng, Jun Liu, Yong Qin, Li Wang, Jie Yang   +4 more
doaj   +1 more source

Hypergraph and network flow-based quality function deployment. [PDF]

Heliyon, 2022
Abonyi J, Czvetkó T.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Network flow and flood routing model for water resources optimization. [PDF]

Sci Rep, 2022
Tahiri A, Che D, Ladeveze D, Chiron P, Archimède B.   +4 more
europepmc   +1 more source

Metric flows with neural networks

Machine Learning: Science and Technology
Abstract We develop a general theory of flows in the space of Riemannian metrics induced by neural network (NN) gradient descent. This is motivated in part by recent advances in approximating Calabi–Yau metrics with NNs and is enabled by recent advances in understanding flows in the space of NNs.
James Halverson, Fabian Ruehle
openaire   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Fluid flow induced calcium response in bone cell network [PDF]

, 2008
In our previous work, bone cell networks with controlled spacing and functional intercellular gap junctions had been successfully established by using microcontact printing and self assembled monolayers technologies [Guo, X. E., E. Takai, X.
Xu Q, Whitesides GM, Guo XE, Costa KD, Hung CT, Huo B(霍波), Lu XL   +6 more
core  

Preface: Hydrology of Large River Basins in Africa [PDF]

Proceedings of the International Association of Hydrological Sciences, 2021
E. Amoussou, E. Amoussou, E. Amoussou, E. Amoussou, G. Mahe, G. Mahe, G. Mahe, O. Amrouni, O. Amrouni, A. Bodian, C. Cudennec, C. Cudennec, S. Dietrich, S. Dietrich, D. J. Kodja, E. W. Vissin   +15 more
doaj   +1 more source

Heterogeneous network flow and Petri nets characterize multilayer complex networks. [PDF]

Sci Rep, 2022
Ademovic Tahirovic A, Angeli D, Strbac G.   +2 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source