Results 101 to 110 of about 74,842 (266)
Interregional Migration Flows in Russia: A Network Approach
Interregional migration in Russia surpasses both intraregional and international migration in vo-lume, playing a pivotal role in redistributing human capital across the country. To capture migration patterns between regions comprehensively, it is crucial
Andrey V. SMIRNOV
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
A NOVEL APPROACH FOR REAL TIME INTERNET TRAFFIC CLASSIFICATION [PDF]
Real time internet traffic classification is imperative for service discrimination, network security and network monitoring. Classification of traffic depends on initial first few network packets of full flows of captured IP traffic.
Rupesh Jaiswal, Shashikant Lokhande
doaj
Metric flows with neural networks
Abstract We develop a general theory of flows in the space of Riemannian metrics induced by neural network (NN) gradient descent. This is motivated in part by recent advances in approximating Calabi–Yau metrics with NNs and is enabled by recent advances in understanding flows in the space of NNs.
James Halverson, Fabian Ruehle
openaire +3 more sources
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Extended Formulations for Order Polytopes through Network Flows. [PDF]
Davis-Stober CP +4 more
europepmc +1 more source

