Results 81 to 90 of about 74,842 (266)
Analyzing the Effect of TCP and Server Population on Massively Multiplayer Games
International Journal of Computer Games Technology, 2014 Many Massively Multiplayer Online Role-Playing Games (MMORPGs) use TCP flows for communication between the server and the game clients. The utilization of TCP, which was not initially designed for (soft) real-time services, has many implications for the ...
Mirko Suznjevic +4 more
doaj +1 more source
IEEE Access, 2019 Hybrid optical-electrical switching based data center network (HOE-DCN) has been regarded as a promising architecture for the next generation data center network (DCN). To achieve traffic optimization, the main superiority of HOE-DCN is its capability to
Yinan Tang +8 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Urban Flow Inference Based on Linear Low-Rank Convolution and Road Network [PDF]
Jisuanji gongchengFine-grained Urban Flow Inference (FUFI) aims to elucidate real fine-grained traffic flows from coarse-grained traffic flows to replace a large number of sensor devices in the real world.
Shulin LIU, Hongjun LI, Yujin GAN, Xiya LUO
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Agent-Based Model for Automaticity Management of Traffic Flows across the Network
Applied Sciences, 2017 This paper presents an agent-based model that performs the management of traffic flows in a network with the purpose of observing in a simulation of distinctive congestion scenarios how the automation of the monitoring task improves the network ...
Karina Raya-Díaz +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Characterizing Multiterminal Flow Networks and Computing Flows in Networks of Small Treewidth
Journal of Computer and System Sciences, 1998 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hagerup, Torben +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source