Results 121 to 130 of about 13,123,772 (306)

Apport du FETP Togo dans la lutte contre les maladies et évènements de santé publique

Journal of Interventional Epidemiology and Public Health
Au lendemain de l’épidémie d’Ebola en Afrique de l’Ouest, la nécessité d’accompagner les ministères de la santé des pays de la sous-région à travers le développement d’une masse critique d’acteurs pour booster la surveillance épidémiologique et la ...
Rébecca Kinde, Takpaya Gnaro, Yendube Douti, Mébiny-Essoh Tchalla Abalo, Wembo Halatoko, Koffi Akolly, Christelle Nikiema, Désiré Lucien Dahourou, Bakaï Tchaa Abalo, Mariame Bonkano Laurent Comlan, Alain Nzanzu Magazani, Virgil Kuassi Lokossou, Pedwinde Hamadou Seogo   +12 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Diagnostic utility of DNA methylation episignature analysis for early diagnosis of KMT2B-related disorders: case report

Frontiers in Genetics
The lysine methyltransferase 2B (KMT2B) gene product is important for epigenetic modifications associated with active gene transcription in normal development and in maintaining proper neural function.
Nadia Bouhamdani, Nadia Bouhamdani, Nadia Bouhamdani, Nadia Bouhamdani, Haley McConkey, Haley McConkey, Amélie Leblanc, Amélie Leblanc, Amélie Leblanc, Bekim Sadikovic, Bekim Sadikovic, Mouna Ben Amor, Mouna Ben Amor, Mouna Ben Amor   +13 more
doaj   +1 more source

Trust and the dynamics of network formation

Network Science
Abstract We evaluate the effect of reciprocal trust within pairs of individuals—gauged by total potential earnings in a trust experiment—on the probability of relationship formation, in comparison with well-known determinants of social ties, such as time of exposure and homophily along demographic traits.
Juan Camilo Cárdenas, Danisz Okulicz, Davide Pietrobon, Tomas Rodriguez-Barraquer, Tatiana Velasco   +4 more
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Investigation d'un cas de rage bovine dans une ferme à Loumbila, Burkina Faso, mai 2022

Journal of Interventional Epidemiology and Public Health
Introduction: La rage est une zoonose prioritaire au Burkina Faso. De 2015 à 2019, 891 cas de rage animale ont été́ enregistrés avec une prédominance chez les chiens et chats.
Aristide Compaoré, Wendlassida Brice Armel Ouédraogo, Martial Touwendsida Nana, Bruno Lalidia Ouoba, Bérenger Kaboré, Denis Yelbéogo   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Connaissances, attitudes et pratiques des parents d’enfants de 12 à 24 mois sur la vaccination dans la Région Maritime au Togo en 2023

Journal of Interventional Epidemiology and Public Health
Introduction : La baisse des couvertures vaccinales notifiées dans la Région Maritime ces trois dernières années constitue un véritable problème de santé publique.
Yao Kataa, Kokou Ayamekpe, Mandjarétou Assih, Takpaya Gnaro, Koffi Akolly, Yamdi Kanou, Titaféi Pouwè Taré, Komlan Aziamadji, Rebecca Mèyè Kinde, Didier Koumavi Ekouevi   +9 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Vascular leukoencephalopathy observed in a patient with fetal alcohol spectrum disorder: An association not yet understood

Brain Disorders
Fetal alcohol spectrum disorder (FASD) encompasses a broad range of physical and neurological impairments resulting from prenatal alcohol exposure (PAE).
Julie Gallien, Nadia Bouhamdani, Mahée Côté, Dominique Bouhamdani, M'Hamed Belkhodja, Nicole Leblanc, Ludivine Chamard-Witkowski   +6 more
doaj   +1 more source