Results 121 to 130 of about 96,335 (304)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Historical Evolution in STI Policy-making in Iran: a Network Governance Approach [PDF]
بهبود مدیریت, 2019 The governance of the STI policy covers a wide range of practices and activities related to complex interactions among different actors in order to converge the conflicting interests in the policy process.
Zohreh Karim Mian +3 more
doaj
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
ARC Governance Research Network
ARC Governance Research Network. Institutions and their governance are frequently part of our most pressing problems - not least in our national research priorities. Hence, institutions are invariably a key part of the solutions.
core
Value creation in brand alliances : a network approach. [PDF]
Alliance; Brand; Governance; Network; Value;
Coulibaly, Mantiaba, Sauvée, Loïc
core
, 2014 In this paper a comparison of the two planned networks that appear in watershed planning documents for the Lake Champlain basin in 2010 One plan (2010 TMDL) was developed by a regulatory network initiated by the United States Environmental Protection ...
Zia, Asim +3 more
core +1 more source
Network governance forms in healthcare: empirical evidence from two Italian cancer networks. [PDF]
BMC Health Serv Res, 2020 Romiti A, Del Vecchio M, Sartor G.
europepmc +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Ecological Smart City Construction Based on Ecological Economy and Network Governance.
Comput Intell Neurosci, 2022 Wu Y.
europepmc +1 more source