Results 81 to 90 of about 15,417,091 (295)
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
International Journal of Management and Network Economics
Expectations of growth of several and differing private and public sectors, especially in light of market liberalisation and increasing attention to quality management, customer satisfaction, technological innovation and value creation, has caused ...
REGGIANI, AURA
core +1 more source
Retracted: Network Management System for IoT Based on Dynamic Systems. [PDF]
Comput Math Methods Med, 2023 Methods In Medicine CAM.
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
BMC Health Services ResearchBackground Post-acute care management programs are designed to optimize transitions from hospitals to skilled nursing facilities (SNFs) and reduce acute care utilization but largely focus on Medicare beneficiaries. Little is known about the effectiveness
Devon Armstrong +9 more
doaj +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Network Revenue Management with Inventory-Sensitive Bid Prices and Customer Choice [PDF]
, 2010 We develop an approximate dynamic programming approach to network revenue management models with customer choice that approximates the value function of the Markov decision process with a non-linear function which is separable across resource inventory ...
Strauss, A K, Meissner, J
core +3 more sources
Denotation and application mechanism of complicated network shared management information model
Tongxin xuebao, 2008 With IP-based environment of complicated network, in order to solve the network management’s problem of system expansibility, multi-domain management, uniform resource description, the method for modeling and using the shared management information model
GAO Zhi-peng +3 more
doaj