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Physical exercise for people with Parkinson's disease: a systematic review and network meta-analysis.

Cochrane Database of Systematic Reviews, 2023
BACKGROUND Physical exercise is effective in managing Parkinson's disease (PD), but the relative benefit of different exercise types remains unclear. OBJECTIVES To compare the effects of different types of physical exercise in adults with PD on the ...
M. Ernst   +12 more
semanticscholar   +1 more source

Efficacy of biological therapies and small molecules in induction and maintenance of remission in luminal Crohn’s disease: systematic review and network meta-analysis

Gut, 2022
Objective There are numerous biological therapies and small molecules licensed for luminal Crohn’s disease (CD), but these are often studied in placebo-controlled trials, meaning relative efficacy is uncertain. We examined this in a network meta-analysis.
B. Barberio   +3 more
semanticscholar   +1 more source

Network Meta-analysis

2018
Meta-analyses of randomized controlled trials have been used for several years to combine data from clinical trials and generate estimates of treatment effect associated with a therapeutic intervention in relation to a comparator. In recent years, there has been an added emphasis on comparative effectiveness research since decision makers are often ...
Joseph C. Cappelleri, William L. Baker
openaire   +1 more source

Comparative Effectiveness of Multiple Different First-Line Treatment Regimens for Helicobacter pylori Infection: a Network Meta-Analysis.

Gastroenterology, 2021
BACKGROUND & AIMS A number of double, triple and quadruple therapies have been proposed as first line H. pylori infection empiric treatments. However, knowledge of their worldwide and regional comparative efficacy is lacking.
T. Rokkas   +8 more
semanticscholar   +1 more source

Network Meta-Analysis

2020
Network meta-analysis is a popular way to combine results from several studies (usually randomized trials) comparing several treatments or interventions. It has usually been performed in a Bayesian setting, but recently it has become possible in a frequentist setting using multivariate meta-analysis and meta-regression, implemented in Stata with mvmeta.
Nikolakopoulou, Adriani   +2 more
openaire   +1 more source

Software to Conduct a Meta-Analysis and Network Meta-Analysis

2021
Statistical software for meta-analysis (MA) and network meta-analysis (NMA) have become indispensable for researchers. The aim of this chapter is to introduce key features of MA and NMA software to compare the effectiveness of interventions. Commonly used or routinely maintained statistical software are reviewed, including commercial and open-sourced ...
Caitlin, Daly, Charlene, Soobiah
openaire   +2 more sources

Transportability in Network Meta-analysis

Epidemiology, 2016
Network meta-analysis is an extension of the conventional pair wise meta-analysis to include treatments that have not been compared head to head. It has in recent years caught the interest of clinical investigators in comparative effectiveness research.
Conrad, Kabali, Marya, Ghazipura
openaire   +2 more sources

Antipsychotic Drugs and Cognitive Function: A Systematic Review and Pairwise Network Meta-Analysis.

JAMA psychiatry
Importance Cognitive deficits are a substantial part of the symptoms of schizophrenia spectrum disorders (SSDs) and contribute heavily to the burden of disease.
le J. Feber   +12 more
semanticscholar   +1 more source

Individual Patient Data Meta-Analysis and Network Meta-Analysis

2021
Meta-analyses are often conducted using trial-level summary data. However, when individual patient data (IPD ) is available, there is greater flexibility in the analysis and a wider range of statistical models that can be fitted. There are two approaches to fitting IPD models.
openaire   +2 more sources

Multiplicative interaction in network meta‐analysis

Statistics in Medicine, 2014
Meta‐analysis of a set of clinical trials is usually conducted using a linear predictor with additive effects representing treatments and trials. Additivity is a strong assumption. In this paper, we consider models for two or more treatments that involve multiplicative terms for interaction between treatment and trial.
Hans-Peter, Piepho   +2 more
openaire   +2 more sources

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