Results 71 to 80 of about 2,283,438 (277)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A Unitary Weights Based One-Iteration Quantum Perceptron Algorithm for Non-Ideal Training Sets

open access: yesIEEE Access, 2019
In order to solve the problem of non-ideal training sets (i.e., the less-complete or over-complete sets) and implement one-iteration learning, a novel efficient quantum perceptron algorithm based on unitary weights is proposed, where the singular value ...
Wenjie Liu   +4 more
doaj   +1 more source

High-density network flow monitoring [PDF]

open access: yes2015 IFIP/IEEE International Symposium on Integrated Network Management (IM), 2015
Monitoring of high-speed networks is becoming a resource intensive task. There are dedicated flow monitoring probes built with commodity hardware support up to 10G links, but multiple 10G or even 100 G optical networks are being used for transport networks and a data center connectivity.
Velan Petr, Puš Viktor
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

An Efficient Scheme for Aggregation and Presentation of Network Performance in Distributed Brokering Systems [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2003
The Internet is presently being used to support increasingly complex interaction models as a result of more and more applications, services and frameworks becoming network centric.
Gurhan Gunduz   +2 more
doaj  

Secret Image Sharing Based on Encrypted Pixels

open access: yesIEEE Access, 2018
The well-known Thien and Lin's (k, n) secret image sharing (SIS) scheme and its extended versions are threshold schemes, in which a secret image is shared among n shadow images and it can be recovered from any k shadow images.
Zhili Zhou   +3 more
doaj   +1 more source

Habitat monitoring with sensor networks [PDF]

open access: yesCommunications of the ACM, 2004
These networks deliver to ecologists data on localized environmental conditions at the scale of individual organisms to help settle large-scale land-use issues affecting animals, plants, and people.
Szewczyk, Robert   +5 more
openaire   +2 more sources

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

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