Results 91 to 100 of about 469,123 (318)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Blue–Green Infrastructure Network Planning in Urban Small Watersheds Based on Water Balance

Land
The rapid expansion of urbanization and inadequate planning have triggered a water balance crisis in many cities, manifesting as both the need for artificial lake supplementation and frequent urban flooding.
Xin Chen, Xiaojun Wang
doaj   +1 more source

Optimization of Virtual Networks

CoRR, 2020
15 ...
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Simple k-Crashing Plan with a Good Approximation Ratio

Mathematics
In project management, a project is typically described as an activity-on-edge network, where each activity/job is represented as an edge of some network N (which is a directed acyclic graph).
Ruixi Luo, Kai Jin, Zelin Ye
doaj   +1 more source

Leveraging AI for Predictive Maintenance with Minimizing Downtime in Telecommunications Networks [PDF]

Iranian Journal of Information Processing & Management
Background: Telecommunications networks are exposed to numerous issues concerning equipment and that causes network outage, which proves very expensive. Basic maintenance methodologies like reactive or even scheduled preventive maintenance cannot cope up
Sarah Ali Abdulkareem, Mohammed Isam Al-Hiyali, Kozhobekov Kudaiberdi Gaparalievich, Saad Jabbar Abbas, Ghanim Magbol Alwan   +4 more
doaj   +1 more source

Multi-Objective Optimization of an Industrial Isoprene Production Unit by Using Genetic Algorithm Approach [PDF]

, 2005
The present work deals with the multi-objective optimization of an industrial Isoprene production unit by using Genetic Algorithm (GA). The purpose of this plant is to produce high purity Isoprene for obtaining synthetic and thermoplastic rubber from a ...
Xavier Joulia, Luiz V. Loureiro, Pascal Floquet, Nascimento, Claudio A. O., Loureiro, Luiz V., Rita M.B. Alves, Joulia, Xavier, Claudio A.O. Nascimento, Floquet, Pascal, Alves, Rita M. B.   +9 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Dynamic Decision-Making for Resource Collaboration in Complex Computing Networks: A Differential Game and Intelligent Optimization Approach

Mathematics
End–edge–cloud collaboration enables significant improvements in system resource utilization by integrating heterogeneous resources while ensuring application-level quality of service (QoS).
Cai Qi, Zibin Zhang
doaj   +1 more source

Optimal-depth sorting networks

Journal of Computer and System Sciences, 2017
We solve a 40-year-old open problem on the depth optimality of sorting networks. In 1973, Donald E. Knuth detailed, in Volume 3 of "The Art of Computer Programming", sorting networks of the smallest depth known at the time for n =< 16 inputs, quoting optimality for n =< 8.
Daniel Bundala, Michael Codish, Luís Cruz-Filipe, Peter Schneider-Kamp, Jakub Závodný   +4 more
openaire   +3 more sources