Results 71 to 80 of about 334,296 (248)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Optical Backplane Based on Ring-Resonators: Scalability and Performance Analysis for 10 Gb/s OOK-NRZ

open access: yesPhotonics, 2014
The use of architectures that implement optical switching without any need of optoelectronic conversion allows us to overcome the limits imposed by today’s electronic backplane, such as power consumption and dissipation, as well as power supply and ...
Giuseppe Rizzelli   +5 more
doaj   +1 more source

Multi-Objective Evolutionary Algorithms to Find Community Structures in Large Networks

open access: yesMathematics, 2020
Real-world complex systems are often modeled by networks such that the elements are represented by vertices and their interactions are represented by edges.
Manuel Guerrero   +4 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

3D Capsule Networks for Object Classification With Weight Pruning

open access: yesIEEE Access, 2020
The proliferation of 3D sensors, due to the increased demand for 3D data, induced the 3D computer vision research in the last decade, and 3D data processing has gained a lot of interest.
Burak Kakillioglu   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

MODIFICATION OF HIERARCHICAL AGGLOMERATIVE CLUSTERING WITH COMPLETE LINKAGE FOR OPTIMAL USAGE WITH PASSIVE OPTICAL NETWORKS

open access: yesActa Polytechnica, 2018
Today, passive optical networks (PONs) represent a modern solution for high-speed FTTx subscriber lines and networks. Due to the fact that optical fibres and cables are deployed in last-mile network segments.
Tomáš Pehnelt   +2 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Identification technology for city freeway users based on XDR big data analysis

open access: yesDianxin kexue, 2021
In the scene of city freeway, the driving speed is relatively faster, the flow of people is denser, and the customers have higher requirements for communication experience.Firstly, the architecture of big data platform for mobile network quality control ...
Baoyou WANG   +3 more
doaj  

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