Results 51 to 60 of about 469,123 (318)

Optimization problems in correlated networks [PDF]

open access: yesComputational Social Networks, 2016
11 pages, 10 figures, accepted for publication in Computational Social Networks ...
Yang, S. (author)   +2 more
openaire   +5 more sources

Cost modelling and validation in network optimization

open access: yes, 2015
There are many costs associated with the build- ing and running a telecommunications network, both capital (CAPEX) and operational (OPEX) costs. On the one hand, complex routing schemes activated in multi-layer networks, like MPLS, logically imply ...
Chang Xing   +11 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Traffic Simulation Models to Enhance Signal Timing in an Oversaturated Network: A Comparative Study of Optimizing Individual Intersections versus the Entire Network

open access: yesInternational Journal of Technology
The objective of this study is to investigate the variations in performance of a network with multiple oversaturated intersections—particularly delays and queue lengths—generated by two different signal timing approaches, namely (i) the classical ...
Punyaanek Srisurin   +2 more
doaj   +1 more source

Artificial Intelligence and Machine Learning in Telecommunications Revolutionizing Customer Experience and Enhancing Service Delivery [PDF]

open access: yesIranian Journal of Information Processing & Management
Background: The telecommunications industry is at the crossroad of change seemingly precipitated by the use of Artificial Intelligence (AI) and Machine Learning (ML).
Yaser Issam Hamodi Aljanabi   +4 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Fault Tolerant Spectral/Spatial Optical Code Division Multiple Access Passive Optical Network

open access: yesSensors
High-capacity communication networks are built to provide high throughput and low latency to accommodate the growing demand for bandwidth. However, the provision of these features is subject to a robust underlying network, which can provide high capacity
Rahat Ullah   +8 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Computing optimal shortcuts for networks [PDF]

open access: yesEuropean Journal of Operational Research, 2019
We study augmenting a plane Euclidean network with a segment, called a shortcut, to minimize the largest distance between any two points along the edges of the resulting network. Problems of this type have received considerable attention recently, mostly for discrete variants of the problem.
Delia Garijo   +3 more
openaire   +13 more sources

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