Results 131 to 140 of about 628,285 (376)

Utilizing network pharmacology to explore the underlying mechanism of Radix Salviae in diabetic retinopathy

open access: yesChinese Medicine, 2019
Introduction Radix Salviae (Dan-shen in pinyin), a classic Chinese herb, has been extensively used to treat diabetic retinopathy in clinical practice in China for many years. However, the pharmacological mechanisms of Radix Salviae remain vague.
Chun-Li Piao   +6 more
doaj   +1 more source

Burst detection methods [PDF]

open access: yesarXiv, 2018
`Bursting', defined as periods of high frequency firing of a neuron separated by periods of quiescence, has been observed in various neuronal systems, both \textit{in vitro} and \textit{in vivo}. It has been associated with a range of neuronal processes, including efficient information transfer and the formation of functional networks during ...
arxiv  

Editorial: Network Pharmacology and Traditional Medicine [PDF]

open access: yesFrontiers in Pharmacology, 2020
Yuanjia Hu   +5 more
openaire   +4 more sources

Peer Review Certifies Quality and Innovation in Clinical Pharmacology & Therapeutics. [PDF]

open access: yes, 2017
Clinical Pharmacology & Therapeutics (CPT) is an established voice of the discipline, a trusted source of new knowledge showcasing discovery, translation, and application of novel therapeutic paradigms to advance the management of patients and ...
Terzic, Andre M., Waldman, Scott A.
core   +2 more sources

Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics

open access: yesAdvanced Biology, EarlyView.
This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim   +3 more
wiley   +1 more source

Integrating network pharmacology, metabolomics, and gut microbiota analysis to explore the effects of Jinhong tablets on chronic superficial gastritis [PDF]

open access: yesarXiv
Chronic superficial gastritis (CSG) severely affects quality of life and can progress to worse gastric pathologies. Traditional Chinese Medicine (TCM) effectively treats CSG, as exemplified by Jinhong Tablets (JHT) with known anti-inflammatory properties, though their mechanism remains unclear.
arxiv  

The Identification of New Pharmacological Targets for the Treatment of Glaucoma: A Network Pharmacology Approach

open access: yesPharmaceuticals
Background: Glaucoma is a progressive optic neuropathy characterized by the neurodegeneration and death of retinal ganglion cells (RGCs), leading to blindness. Current glaucoma interventions reduce intraocular pressure but do not address retinal neurodegeneration.
Giuffrida E.   +6 more
openaire   +4 more sources

Electrospinning Technology, Machine Learning, and Control Approaches: A Review

open access: yesAdvanced Engineering Materials, Volume 27, Issue 7, April 2025.
Electrospinning produces micro‐ and nanoscale fibers, holding great promise in biomedical engineering. Industrial adoption faces challenges in controlling fiber properties, reproducibility, and scalability. This review explores electrospinning techniques, modeling, and machine learning for process optimization.
Arya Shabani   +5 more
wiley   +1 more source

A computational study on synaptic and extrasynaptic effects of astrocyte glutamate uptake on orientation tuning in V1 [PDF]

open access: yesarXiv, 2017
Astrocytes affect neural transmission by a tight control via glutamate transporters on glutamate concentrations in direct vicinity to the synaptic cleft and by extracellular glutamate. Their relevance for information representation has been supported by in-vivo studies in ferret and mouse primary visual cortex.
arxiv  

Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo [PDF]

open access: green, 2006
Mercedes Amat   +7 more
openalex   +1 more source

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