Results 131 to 140 of about 17,342 (262)

Exploring the In Vitro Mechanism of Action of β-Acetoxyisovalerylalkannin on Inflammatory Skin Diseases Using Network-Based Pharmacology and Non-Targeted Metabolomics

Objective: Lithospermum erythrorhizon has been extensively used for the clinical treatment of skin diseases, but its material basis and mechanism of action remain unclear.
Jinyan Li, Liuqian Peng, Yinglan Ma, Yue Ma, Jianguang Li, Xuehong Ma, Lu Zhang, Zixin Zhang   +7 more
core   +1 more source

Editorial: Network Pharmacology and Traditional Medicine [PDF]

Frontiers in Pharmacology, 2020
Xinxing Lai, Xin Wang, Yuanjia Hu, Shibing Su, Wenqing Li, Shao Li   +5 more
openaire   +3 more sources

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

Advanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco, Valerio Francesco Annese, Valerio Galli, Ilaria Penna, Debora Russo, Marina Veronesi, Rita Scarpelli, Stefania Sabella, Mario Caironi   +8 more
wiley   +1 more source

Molecular Mechanism of Sangmei Zhike Granules in Treating Allergic Asthma: Insights from UPLC-MS/MS and Network Pharmacology

Natural Product Communications
Background: Asthma has become an increasingly serious and prevalent public health issue. Chinese herbal medicine holds promising potential as an adjunctive therapy for asthma.
Kai Li, Shi-yu Zhang, Gui-rui Huang, Hong-sheng Cui   +3 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Network Pharmacology Combined With Metabolomics Reveals the Mechanism of Yangxuerongjin Pill Against Type 2 Diabetic Peripheral Neuropathy in Rats

Ran Jin,* Hailuan Pei,* Feng Yue, Xiaodi Zhang, Zhicong Zhang, Yi Xu, Jinsheng Li Beijing Tongrentang Technology Development Co., Ltd. Pharmaceutical Factory, Beijing, 100079, People’s Republic of China*These authors contributed equally to ...
Yue F, Li J, Jin R, Zhang Z, Zhang X, Pei H, Xu Y   +6 more
core  

A network pharmacology approach to discover active compounds and action mechanisms of San-Cao Granule for treatment of liver fibrosis

, 2016
Shizhang Wei,1,2 Ming Niu,3 Jian Wang,2 Jiabo Wang,3 Haibin Su,4 Shengqiang Luo,5 Xiaomei Zhang,2,6 Yanlei Guo,6 Liping Liu,1 Fengqun Liu,1 Qingguo Zhao,1 Hongge Chen,1 Xiaohe Xiao,3 Pan Zhao,4,7 Yanling Zhao1,2 1Department of Pharmacy, 302 Hospital of ...
Liu L, Guo Y, Xiao X, Chen H, Wang J, Su H, Zhao Y, Zhao Q, Wei S, Zhang X, Zhao P, Niu M, Luo S, Liu F   +13 more
core  

Network pharmacology-based investigation of the pharmacological mechanisms of diosgenin in nonalcoholic steatohepatitis

Scientific Reports
The prevalence of nonalcoholic steatohepatitis (NASH) is rising annually, posing health and economic challenges, with limited treatments available. Diosgenin, a natural steroidal compound found in various plants, holds potential as a therapeutic candidate. Recent studies have confirmed diosgenin's anti-inflammatory and metabolism-modulating properties.
Peiyuan Gu, Juan Chen, Jingxin Xin, Huiqi Chen, Ran Zhang, Dan Chen, Yuhan Zhang, Shanshan Shao   +7 more
openaire   +3 more sources

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source

Network pharmacology in food-medicine homology: AI-driven decoding of multi-target synergy from molecular networks to precision health

Acupuncture and Herbal Medicine
Network pharmacology provides a transformative framework for decoding multi-target, system-level mechanisms of the food-medicine homology (FMH) substances, overcoming the limitations of reductionist approaches by integrating multi-omics data ...
Deyang Sun, Pan Chen, Li Tao, Peng Ma, Lichong Meng, Shuting Yin, Bo Zhang, Shao Li   +7 more
doaj   +1 more source