Results 141 to 150 of about 628,285 (376)
Advanced Functional Materials, EarlyView.Transarterial Chemoembolization (TACE) may aggravate liver fibrosis. In this study, a novel oral targeting nanoemulsion is fabricated to enhance the therapeutic effect of antifibrotic drug‐pirfenidone (PFD) on fibrosis after TACE. Studies have shown that PFD nanoemulsion can enhance the oral liver targeting effect of PFD, and effectively improve the ...
Zhimei Cheng +12 more
wiley +1 more source
Chinese MedicineThe application of network formulaology and network pharmacology has significantly advanced the scientific understanding of traditional Chinese medicine (TCM) treatment mechanisms in disease.
Yishu Liu +7 more
doaj +1 more source
Molecules, 2019 Type 2 diabetes mellitus (T2DM) is a metabolic disease accompanied by a series of diseases such as diabetic nephropathy. The drug pair (HS) of Astragalus Radix (HQ) and Dioscoreae Rhizoma (SY) was designed by Dr.
Qian Guo +6 more
doaj +1 more source
Jefferson Alumni Bulletin – Volume XLVI, Number 3, June 1997 [PDF]
, 1997 Jefferson Alumni Bulletin – Volume XLVI, Number 3, June 1997 Dermatology and Cutaneous Biology, Page 4 Mutations in Cornea-Specific Proteins Are Cause of Fragile Eye Disease, Page 8 Albert Einstein Healthcare Network Becomes a Founding Member of the ...
core +1 more source
Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine
Advanced Functional Materials, Volume 35, Issue 20, May 16, 2025.Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang +5 more
wiley +1 more source
Botanical Drugs, Synergy, and Network Pharmacology: Forth and Back to Intelligent Mixtures [PDF]
, 2011 Jürg Gertsch
openalex +1 more source
HD Physiology Project-Japanese efforts to promote multilevel integrative systems biology and physiome research. [PDF]
, 2017 The HD Physiology Project is a Japanese research consortium that aimed to develop methods and a computational platform in which physiological and pathological information can be described in high-level definitions across multiple scales of time and size.
for HD physiology project investigators +3 more
core
Advanced Functional Materials, EarlyView.The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang +9 more
wiley +1 more source
A deep graph model for the signed interaction prediction in biological network [PDF]
arXivPredicting signed interactions in biological networks is crucial for understanding drug mechanisms and facilitating drug repurposing. While deep graph models have demonstrated success in modeling complex biological systems, existing approaches often fail to distinguish between positive and negative interactions, limiting their utility for precise ...
arxiv
Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations
Advanced Functional Materials, EarlyView.Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan +4 more
wiley +1 more source