Results 201 to 210 of about 7,014,814 (396)

Material Basis of Chinese Herbal Formulas Explored by Combining Pharmacokinetics with Network Pharmacology

, 2013
Lixia Pei, Yuanwu Bao, Sheng Liu, Jin Zheng, Xiuping Chen   +4 more
openalex   +2 more sources

Upconversion Nanoparticle‐Covalent Organic Framework Core–shell Particles as Therapeutic Microrobots Trackable With Optoacoustic Imaging

Advanced Materials, EarlyView.
Upconversion nanoparticle‐covalent organic framework core–shell particles provide enhanced contrast for optoacoustic imaging by leveraging the optical absorption of upconversion luminescence within the covalent organic framework matrix. Beyond their role as contrast agents, these particles enable customizable therapeutic agent loading and release, as ...
Dong Wook Kim, Paul Wrede, Andrés Rodríguez‐Camargo, Yi Chen, Nihal Olcay Dogan, Chaim Glück, Bettina V. Lotsch, Daniel Razansky, Metin Sitti   +8 more
wiley   +1 more source

Danhong injection alleviates OGD-induced blood-brain barrier injury via VEGFR2/PI3K/AKT pathway based on network pharmacology and experimental evidence

Journal of Holistic Integrative Pharmacy
Objective: Previous studies have shown that Danhong injection (DHI) has a protective effect on the blood-brain barrier (BBB) function after ischemic stroke.
Yutong Zhang, Meixia Xie, Jiayin Liang, Li Li, Shumei Wang, Minghua Xian   +5 more
doaj  

Comparing the effectiveness profile of pharmacological interventions used for orthodontic pain relief: an arm-based multilevel network meta-analysis of longitudinal data [PDF]

, 2016
Satpal S. Sandhu, Hans‐Peter Piepho, Harpreet S. Khehra   +2 more
openalex   +1 more source

De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

Advanced Materials, EarlyView.
NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang, Jordi Guillem‐Marti, Saurav Kumar, David S. Lee, Daniel Cabrerizo‐Aguado, Rachel Werther, Kevin Alexander Estrada Alamo, Yan Ting Zhao, Adam Nguyen, Irina Kopyeva, Buwei Huang, Jing Li, Yuxin Hao, Xinting Li, Aritza Brizuela‐Velasco, Analisa Murray, Stacey Gerben, Anindya Roy, Cole A. DeForest, Timothy Springer, Hannele Ruohola‐Baker, Jonathan A. Cooper, Melody G. Campbell, Jose Maria Manero, Maria‐Pau Ginebra, David Baker   +25 more
wiley   +1 more source

Comparative efficacy and safety of pharmacologic interventions for cachexia: A systematic review and network meta-analysis [PDF]

, 2017
Manit Saeteaw, Suphat Subongkot, Nathorn Chaiyakunapruk   +2 more
openalex   +1 more source

Active Biopaste for Coral Reef Restoration

Advanced Materials, EarlyView.
Preserving coral reefs is essential. A conductive, hardening paste for coral attachment and mineral accretion technology is developed, using a bio‐based acrylate soybean oil matrix and graphene nanoplatelets. Corals are attached with and onto the conductive paste, electricity is applied, water electrolysis is induced, and calcium is deposited at the ...
Gabriele Corigliano, Valerio Isa, Valerio Francesco Annese, Camilla Rinaldi, Maria Summa, Rosalia Bertorelli, Paolo Galli, Silvia Lavorano, Mario Caironi, Marco Contardi, Pietro Cataldi, Simone Montano, Athanassia Athanassiou   +12 more
wiley   +1 more source

Systemic pharmacological treatments for chronic plaque psoriasis: a network meta-analysis [PDF]

, 2017
É. Sbidian, Anna Chaimani, I. García‐Doval, Giao Do, Camille Hua, Canelle Mazaud, C. Droitcourt, Carolyn Hughes, J.R. Ingram, Luigi Naldi, O. Chosidow, Laurence Le Cleach   +11 more
openalex   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

Network pharmacology and experimental evidence: MAPK signaling pathway is involved in the anti-asthma roles of Perilla frutescens leaf

Heliyon
Perilla frutescens (PF) leaf is a traditional Chinese medicine and food with beneficial effects on allergic asthma. We sought to elucidate the active compounds, the targets, and underlying mechanisms of PF leaf in the treatment of allergic asthma by ...
Mingzhuo Cao, Mengling Zhan, Heyun Jing, Zeqian Wang, Yuan Wang, Xiumin Li, Mingsan Miao   +6 more
doaj