Results 71 to 80 of about 1,289,066 (290)
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
An enhanced Multipath Strategy in Mobile Ad hoc Routing Protocols
, 2018 The various routing protocols in Mobile Ad hoc Networks follow different strategies to send the information from one node to another. The nodes in the network are non static and they move randomly and are prone to link failure which makes always to find ...
Alfawaer, Zeyad M. +1 more
core +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Технологія та конструювання в електронній апаратурі, 2005 A model of a technological network has been proposed and software developed for monitoring parameters and controlling the modes of the technological process of semiconductor crystal and thin-film growth.
R. V. Rogov +2 more
doaj
, 2014 This paper analyzes the performance of the primary and secondary users (SUs) in an arbitrarily-shaped underlay cognitive network. In order to meet the interference threshold requirement for a primary receiver (PU-Rx) at an arbitrary location, we consider
Durrani, Salman +2 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Communication protocols for wireless sensor networks: A survey and comparison
Heliyon, 2019 Studies conducted on resource management in wireless sensor networks have identified energy efficient routing protocols as one of the energy saving mechanisms that can be used to manage the consumption of networks’ available energy and extend network ...
Lucia Keleadile Ketshabetswe +4 more
doaj +1 more source
Reinterpreting the transport protocol stack to embrace ossification [PDF]
, 2015 Ubiquitous deployment of middleboxes has resulted in ossification of the transport layer, with TCP and UDP becoming part of the narrow waist of the Internet.
McQuistin, Stephen, Perkins, Colin
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source