Results 141 to 150 of about 32,401,733 (254)
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Temporal visitation patterns of points of interest in cities on a planetary scale: a network science and machine learning approach. [PDF]
Sci Rep, 2023 Betancourt F, Riascos AP, Mateos JL.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Network science inspires novel tree shape statistics. [PDF]
PLoS One, 2021 Chindelevitch L +3 more
europepmc +1 more source
Catholic Women's Network, September / October, 1989
, 1989 Digitized version of a newspaper published by the Catholic Women's Network (CWN), a non-profit educational organization for women's spirituality and personal growth.
Catholic Women's Network (Sunnyvale, Calif);
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Interregional Migration Flows in Russia: A Network Approach
AlterEconomicsInterregional migration in Russia surpasses both intraregional and international migration in vo-lume, playing a pivotal role in redistributing human capital across the country. To capture migration patterns between regions comprehensively, it is crucial
Andrey V. SMIRNOV
doaj +1 more source
Catholic Women's Network, November / December, 1990
, 1990 Digitized version of a newspaper published by the Catholic Women's Network (CWN), a non-profit educational organization for women's spirituality and personal growth.
Catholic Women's Network (Sunnyvale, Calif);
core
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Carrier Transport in Colloidal Quantum Dot Intermediate Band Solar Cell Materials Using Network Science. [PDF]
Int J Mol Sci, 2023 Cuadra L +2 more
europepmc +1 more source