Results 101 to 110 of about 151,952 (268)

Evaluating the impact of MR image harmonization on thalamus deep network segmentation. [PDF]

Proc SPIE Int Soc Opt Eng, 2022
Shao M, Zuo L, Carass A, Zhuo J, Gullapalli RP, Prince JL.   +5 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

A Method for Surface Defect Detection Based on Multiscale Feature Fusion and Pyramid Attention

IEEE Access
The two-stage defect detection model needs to pay attention to the results of the segmentation network and the classification network, and the results of the segmentation network will have an impact on the classification network.
Ying Tang, Hongyuan Wang, Qunying Zhou, Boyan Sun   +3 more
doaj   +1 more source

3D deep convolutional neural network segmentation model for precipitate and porosity identification in synchrotron X-ray tomograms. [PDF]

J Synchrotron Radiat, 2022
Gaudez S, Ben Haj Slama M, Kaestner A, Upadhyay MV.   +3 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Exploration of CT Images Based on the BN-U-net-W Network Segmentation Algorithm in Glioma Surgery. [PDF]

Contrast Media Mol Imaging, 2022
Yu Y, Du Z, Yuan C, Li J.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

The impact of transfer learning on 3D deep learning convolutional neural network segmentation of the hippocampus in mild cognitive impairment and Alzheimer disease subjects. [PDF]

Hum Brain Mapp, 2022
Balboni E, Nocetti L, Carbone C, Dinsdale N, Genovese M, Guidi G, Malagoli M, Chiari A, Namburete AIL, Jenkinson M, Zamboni G.   +10 more
europepmc   +1 more source

Uncertainty-Guided Segmentation Network for Geospatial Object Segmentation

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Geospatial objects pose significant challenges, including dense distribution, substantial interclass variations, and minimal intraclass variations. These complexities make achieving precise foreground object segmentation in high-resolution remote sensing images highly challenging.
Hongyu Jia, Wenwu Yang, Lin Wang 0100, Haolin Li   +3 more
openaire   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source