Results 101 to 110 of about 3,134,512 (293)

Collective dynamical response of coupled oscillators with any network structure

open access: yes, 2008
We formulate a reduction theory that describes the response of an oscillator network as a whole to external forcing applied nonuniformly to its constituent oscillators.
A. Pikovsky   +10 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Efficient marine predators algorithm for solving multidimensional complex functions and real-world engineering design problems

open access: yes工程科学学报
As optimization problems grow increasingly complex, characterized by their intricate difficulty, larger-scale, and diverse constraints, swarm intelligence optimization algorithms have emerged as an effective solution for addressing these multifaceted ...
Jingsen LIU   +3 more
doaj   +1 more source

Construction of Neural Network Classification Expert Systems Using Switching Theory Algorithms [PDF]

open access: yes, 1992
A new family of neural network architectures is presented. This family of architectures solves the problem of constructing and training minimal neural network classification expert systems by using switching theory.
Jaskolski, John V.
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

A Cross-Layer Approach to Analyzing Energy Consumption and Lifetime of a Wireless Sensor Node

open access: yesJournal of Sensor and Actuator Networks
Several wireless communication technologies, including Wireless Sensor Networks (WSNs), are essential for Internet of Things (IoT) applications. WSNs employ a layered framework to govern data exchanges between sender and recipient, which facilitates the ...
Fernando Ojeda   +4 more
doaj   +1 more source

Frictional Unemployment on Labor Flow Networks

open access: yes, 2019
We develop an alternative theory to the aggregate matching function in which workers search for jobs through a network of firms: the labor flow network. The lack of an edge between two companies indicates the impossibility of labor flows between them due
Axtell, Robert L.   +2 more
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Improving audit functions of supreme audit institutions to promote sustainable development

open access: yesApstract: Applied Studies in Agribusiness and Commerce, 2012
In this paper, we demonstrate and analyze the substance of the added value effect of a Supreme Audit Institution (SAI), focusing on sustainable development issues.We intend to answer such questions as: how could a SAI respond to global and local ...
Sándor Nagy   +2 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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