Results 111 to 120 of about 3,134,512 (293)
Wideband BPSK Transmitter Phased Array Operating at 246 GHz With ±30° Steering Range
IEEE AccessThis paper presents the construction and measurement of a phased array BPSK transmitter system operating at 246 GHz with tested data rates of up to 32 Gbit s-1.
Joachim Hebeler +3 more
doaj +1 more source
Vietnam’s Connectivity and Embeddedness in the Maritime Silk Road and Global Maritime Network
IEEE Access, 2019 Vietnam is one of the sixty-five countries in the belt and road (BR) initialized by China and especially an important player along the 21st century maritime silk road (MSR).
Zhi-Hua Hu
doaj +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
The (Elusive) Theory of Everything [PDF]
, 2010 Stephen Hawking's work on black holes and the origin of the universe is arguably the most concrete progress theoretical physicists have made toward reconciling Einstein's gravitation and quantum physics into one final theory of everything.
Hawking, Stephen, Mlodinow, Leonard
core
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
The Effects of Aging and Cognition on Gait Coordination Analyzed Through a Network Analysis Approach
BiomechanicsBackground/Objectives: Walking coordination is crucial for maintaining independence and quality of life, but it is significantly affected by aging and cognitive decline.
Mario De Luca +7 more
doaj +1 more source