Results 51 to 60 of about 391,710 (263)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Impact of Frequency Heterogeneity on Mutually Synchronized Spatially Distributed 24 GHz PLLs

open access: yesIEEE Open Journal of Circuits and Systems
This research analyzes the mutual self-organized synchronization of phase-locked loops (PLLs) in the presence of variations in the free-running frequency of a PLL.
Christian Hoyer   +2 more
doaj   +1 more source

Mean First-Passage Time on Scale-Free Networks Based on Rectangle Operation

open access: yesFrontiers in Physics, 2021
The mean first-passage time of random walks on a network has been extensively applied in the theory and practice of statistical physics, and its application effects depend on the behavior of first-passage time. Here, we firstly define a graphic operation,
Xiaomin Wang   +4 more
doaj   +1 more source

Classical information theory of networks

open access: yesJournal of Physics: Complexity, 2020
AbstractExisting information-theoretic frameworks based on maximum entropy network ensembles are not able to explain the emergence of heterogeneity in complex networks. Here, we fill this gap of knowledge by developing a classical framework for networks based on finding an optimal trade-off between the information content of a compressed representation
Filippo Radicchi   +3 more
openaire   +2 more sources

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Modulation Bandwidth Investigation of Voltage-Controlled Oscillators Under Periodic Linear Frequency Modulation

open access: yesIEEE Open Journal of Circuits and Systems
The modulation bandwidth of a voltage-controlled oscillator (VCO) is a key design metric that defines its ability to respond to fast tuning voltages and change its frequency accordingly. While prior works have addressed practical methods for measuring it,
Rabia Fatima Riaz   +2 more
doaj   +1 more source

Homophyly Networks -- A Structural Theory of Networks

open access: yesCoRR, 2013
A grand challenge in network science is apparently the missing of a structural theory of networks. The authors have showed that the existence of community structures is a universal phenomenon in real networks, and that neither randomness nor preferential attachment is a mechanism of community structures of network \footnote{A. Li, J. Li, and Y.
Angsheng Li   +2 more
openaire   +2 more sources

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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