Results 61 to 70 of about 3,134,512 (293)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Signed Network Modeling Based on Structural Balance Theory

open access: yes, 2018
The modeling of networks, specifically generative models, have been shown to provide a plethora of information about the underlying network structures, as well as many other benefits behind their construction.
Beigi Ghazaleh   +4 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Designing a Power and Speed Adaptive 60 GHz Receiver in 22 nm FD-SOI CMOS for Tactile Internet Applications

open access: yesIEEE Access
This research presents and examines the first power and speed adaptive 60 GHz receiver, combining the potential of high data rates with low energy consumption.
Helmuth P. E. Morath   +6 more
doaj   +1 more source

Mean Field Theory For Non-Equilibrium Network Reconstruction

open access: yes, 2011
There has been recent progress on the problem of inferring the structure of interactions in complex networks when they are in stationary states satisfying detailed balance, but little has been done for non-equilibrium systems.
Hertz, John A., Roudi, Yasser
core   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Energy-Efficient Aggressive Duty-Cycling of V-Band Power Amplifiers

open access: yesIEEE Access
In addition to implementing the core functionality, a design goal for modern circuits is reduced energy consumption. When options for improving active state efficiency are eventually exhausted, the next step is to aggressively minimize the duration a ...
Maximilian Gottfried Becker   +3 more
doaj   +1 more source

Exploring continuous organisational transformation as a form of network interdependence [PDF]

open access: yes, 2008
In this paper we examine the problematic area of continuous transformation. We conduct our analysis from three theoretical perspectives: the resource based view, social network theory, and stakeholder theory. We found that the continuous transformation
Braganza, A, Stebbings, H
core  

Network Goods (Theory)

open access: yes, 2008
Network effects arise where current users of a good gain when additional users adopt it (classic examples are telephones and faxes). The effects create multiple equilibria and fierce competition between incompatible networks; users' expectations are crucial in determining which network succeeds.
openaire   +1 more source

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