Results 61 to 70 of about 391,710 (263)

Evaluating the Reproducibility of Single-Cell Gene Regulatory Network Inference Algorithms

Frontiers in Genetics, 2021
Networks are powerful tools to represent and investigate biological systems. The development of algorithms inferring regulatory interactions from functional genomics data has been an active area of research.
Yoonjee Kang, Denis Thieffry, Laura Cantini   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Designing a Power and Speed Adaptive 60 GHz Receiver in 22 nm FD-SOI CMOS for Tactile Internet Applications

IEEE Access
This research presents and examines the first power and speed adaptive 60 GHz receiver, combining the potential of high data rates with low energy consumption.
Helmuth P. E. Morath, Xin An, Matthias Jobst, Mengqi Cui, Jens Wagner, Christian Mayr, Frank Ellinger   +6 more
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Energy-Efficient Aggressive Duty-Cycling of V-Band Power Amplifiers

IEEE Access
In addition to implementing the core functionality, a design goal for modern circuits is reduced energy consumption. When options for improving active state efficiency are eventually exhausted, the next step is to aggressively minimize the duration a ...
Maximilian Gottfried Becker, Marco Gunia, Diego Mendez, Frank Ellinger   +3 more
doaj   +1 more source

Network Goods (Theory)

, 2008
Network effects arise where current users of a good gain when additional users adopt it (classic examples are telephones and faxes). The effects create multiple equilibria and fierce competition between incompatible networks; users' expectations are crucial in determining which network succeeds.
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Channel Sounding: Metrological Exploration of the Design Options Using Related Positioning Systems

IEEE Access
Bluetooth® channel sounding, which has recently found its way into the first integrated circuits, is a method for accurate distance estimation between Bluetooth® devices using phase-based concepts and time of flight.
Marco Gunia, Frank Ellinger
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

A 60 GHz Broadband LNA With Joined Variable Gain Control and Switching in 22 nm FD-SOI

IEEE Access
This paper investigates a 60 GHz low-power broadband low noise amplifier (LNA) with variable gain control. To prove the concept, the circuit is implemented in a 22nm fully depleted silicon on insulator (FD-SOI) CMOS technology.
Xin Xu, Jens Wagner, Corrado Carta, Frank Ellinger   +3 more
doaj   +1 more source