Results 61 to 70 of about 7,107,100 (382)

Heating network topology

open access: yesJournal of Physics: Conference Series, 2020
The article proposes an algorithm for the topology of the heat network by generating trees of the initial redundant heat network diagram, conducting a directed search of possible system states. The technique allows you to choose the optimal configuration
N. Yegorova, A. Yakovlev, A. Nikiforov
semanticscholar   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Key Features of Turing Systems are Determined Purely by Network Topology [PDF]

open access: yesPhysical Review X, 2017
Turing's theory of pattern formation is a universal model for self-organization, applicable to many systems in physics, chemistry and biology. Essential properties of a Turing system, such as the conditions for the existence of patterns and the ...
Xavier Diego   +3 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Reactive explorers to unravel network topology [PDF]

open access: yes, 2018
A procedure is developed and tested to recover the distribution of connectivity of an a priori unknown network, by sampling the dynamics of an ensemble made of reactive walkers.
Adam, Ihusan   +3 more
core   +2 more sources

Identification of excitatory-inhibitory links and network topology in large-scale neuronal assemblies from multi-electrode recordings

open access: yesPLoS Comput. Biol., 2018
Functional-effective connectivity and network topology are nowadays key issues for studying brain physiological functions and pathologies. Inferring neuronal connectivity from electrophysiological recordings presents open challenges and unsolved problems.
Vito Paolo Pastore   +3 more
semanticscholar   +1 more source

Network Topology in Soft Gels: Hardening and Softening Materials. [PDF]

open access: yesLangmuir, 2017
The structural complexity of soft gels is at the origin of a versatile mechanical response that allows for large deformation, controlled elastic recovery, and toughness in the same material.
M. Bouzid, E. Del Gado
semanticscholar   +1 more source

Intuitive network topology

open access: yesJournal of Experimental Psychology: General
Topology is the branch of mathematics that seeks to understand and describe spatial relations. A number of studies have examined the human perception of topology — in particular, whether adults and young children perceive and differentiate objects based on features like closure, boundedness, and emptiness. Topology is about more than ‘wholes and holes’,
Sami Ryan Yousif, Elizabeth M. Brannon
openaire   +2 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Empirical analysis of the ship-transport network of China

open access: yes, 2007
Structural properties of the ship-transport network of China (STNC) are studied in the light of recent investigations of complex networks. STNC is composed of a set of routes and ports located along the sea or river.
Feng Liu   +3 more
core   +1 more source

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