Results 71 to 80 of about 4,938,948 (296)

Topology of deep neural networks

open access: yesJ. Mach. Learn. Res., 2020
We study how the topology of a data set $M = M_a \cup M_b \subseteq \mathbb{R}^d$, representing two classes $a$ and $b$ in a binary classification problem, changes as it passes through the layers of a well-trained neural network, i.e., with perfect accuracy on training set and near-zero generalization error ($\approx 0.01\%$). The goal is to shed light
Gregory Naitzat   +2 more
openaire   +4 more sources

Resilient functioning is associated with altered structural brain network topology in adolescents exposed to childhood adversity

open access: yes, 2023
Childhoodadversityis oneofthestrongestpredictors ofadolescentmentalillness.Therefore, it is critical that the mechanisms thataid resilient functioning in individuals exposed to childhood adversity are better understood.
Van Harmelen, Anne Laura   +8 more
core   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

open access: yesFEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan   +2 more
wiley   +1 more source

Generative Topological Networks

open access: yesCoRR
Generative methods have recently seen significant improvements by generating in a lower-dimensional latent representation of the data. However, many of the generative methods applied in the latent space remain complex and difficult to train. Further, it is not entirely clear why transitioning to a lower-dimensional latent space can improve generative ...
Alona Levy-Jurgenson, Zohar Yakhini
openaire   +2 more sources

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Attopo: An SDN Non-Protocol Topology Discovery Method Based on Attention Mechanism and Network Flow Analysis

open access: yesIEEE Access
In an SDN environment, topology discovery is a key function that allows the network controller to accurately understand how network devices are connected and interact.
Tianyi Zhang, Yong Wang
doaj   +1 more source

Topology Dynamics in a P2PTV Network [PDF]

open access: yes, 2009
In recent years, a number of commercial peer-to-peer TV (P2PTV) applications have been launched. Yet, their mechanisms and characteristics are unknown. In this paper, we study SopCast, a typical proprietary P2PTV system. Treating SopCast as a black box, we perform a set of experiments that are suitable to analyze SopCast in depth.
Tang, S. (author)   +4 more
openaire   +2 more sources

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

open access: yesFEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi   +6 more
wiley   +1 more source

Configuration and innovation related network topology

open access: yesJournal of Innovation & Knowledge, 2016
Network topologies attract much theoretical attention in recent studies. Researchers adopt network topology models and assert that specific type of network topology improves product and process innovation.
Ela Ozkan-Canbolat, Aydin Beraha
doaj   +1 more source

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

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