Results 101 to 110 of about 235,780 (318)
Investigation of the tolerance of wavelength-routed optical networks to traffic load variations. [PDF]
, 2006 This thesis focuses on the performance of circuit-switched wavelength-routed optical network with unpredictable traffic pattern variations. This characteristic of optical networks is termed traffic forecast tolerance.
Lao, Ningning, Lao, N.
core
Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz +3 more
wiley +1 more source
Complex Network Traffic Signal Optimized Model and Simulation [PDF]
, 2015 In urban road traffic system, an important issue with the expansion of the network, resulting in the increasing complexity of the network, in-depth analysis of complex network operating mechanism is to further optimize and control network traffic and ...
Bi X(毕欣) +3 more
core
SensorsInternet of Things (IoT) applications and resources are highly vulnerable to flood attacks, including Distributed Denial of Service (DDoS) attacks.
Farhan Ullah +4 more
doaj +1 more source
Annals of Clinical and Translational Neurology, EarlyView.Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao +6 more
wiley +1 more source
A study of self-similar traffic generation for ATM networks [PDF]
, 1997 This thesis discusses the efficient and accurate generation of self-similar traffic for ATM networks. ATM networks have been developed to carry multiple service categories.
Chen, Hung-Ming, Chen, H.
core
Cracking the Code: Genotype–Phenotype Correlation Models in Sarcoglycanopathies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Sarcoglycanopathies are among the most severe limb‐girdle muscular dystrophies (LGMD), though milder presentations have been described. These diseases are primarily caused by missense variants, but the limited predictability of their effect on protein maturation, complex formation, and transport has hindered reliable genotype ...
Leonela Luce +72 more
wiley +1 more source
Traffic Management in Isochronets Networks [PDF]
, 2000 This paper presents an evaluation of a traffic management mechanism for high speed networks called RDMA (Route Division Multiple Access), developed as part of the Isochronets, a novel architecture for high speed networks. RDMA enables routes to designated destinations during time intervals (green-bands) available periodically.
Kelvin Lopes Dias +2 more
openaire +1 more source
SPG4 and Dementia: Expanding the Clinical Spectrum
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza +19 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source