Results 21 to 30 of about 978,890 (244)

Traffic on complex networks: Towards understanding global statistical properties from microscopic density fluctuations [PDF]

open access: yes, 2004
We study the microscopic time fluctuations of traffic load and the global statistical properties of a dense traffic of particles on scale-free cyclic graphs.
A. Arenas   +19 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Network link dimensioning : a measurement & modeling based approach [PDF]

open access: yes, 2006
Adequate network link dimensioning requires a thorough insight into the interrelationship between: (i) the traffic offered (in terms of the average load, but also its fluctuations), (ii) the desired level of performance, and (iii) the required bandwidth ...
Meent, Remco van de
core   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Towards Steganography Detection Through Network Traffic Visualisation

open access: yes, 2012
The paper presents initial step toward new network anomaly detection method that is based on traffic visualisation. The key design principle of the proposed approach is the lack of direct, linear time dependencies for the created network traffic ...
Jankowski, Bartosz   +2 more
core   +1 more source

Performance Comparison of Contention- and Schedule-based MAC Protocols in Urban Parking Sensor Networks [PDF]

open access: yes, 2014
Network traffic model is a critical problem for urban applications, mainly because of its diversity and node density. As wireless sensor network is highly concerned with the development of smart cities, careful consideration to traffic model helps choose
Lin, Trista   +2 more
core   +4 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Optimizing Traffic Lights in a Cellular Automaton Model for City Traffic

open access: yes, 2001
We study the impact of global traffic light control strategies in a recently proposed cellular automaton model for vehicular traffic in city networks.
A. Schadschneider   +30 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

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