Results 51 to 60 of about 112,253 (268)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

NETWORK TRAFFIC FORCASTING IN INFORMATION-TELECOMMUNICATION SYSTEM OF PRYDNIPROVSK RAILWAYS BASED ON NEURO-FUZZY NETWORK

Nauka ta progres transportu, 2016
Purpose. Continuous increase in network traffic in the information-telecommunication system (ITS) of Prydniprovsk Railways leads to the need to determine the real-time network congestion and to control the data flows.
V. M. Pakhomovа
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Joint Optimization of Passenger Flow Control and Train Skip-Stopping for Overcrowded Metro Lines: A Multi-Agent Reinforcement Learning Approach

Urban Rail Transit
During rush hours, the capacity of metro in megacities is insufficient to meet the travel demand, resulting in oversaturation and high risk on platform in stations, especially transfer stations.
Siqiao Xing, Jianyuan Guo, Yong Qin, Limin Jia, Yueyue Wang, Shuning Jiang   +5 more
doaj   +1 more source

Instance Based Classification for Decision Making in Network Data

Journal of Intelligent Systems, 2012
Network data analysis helps in capturing node usage behavior. Existing algorithms use reduced feature set to manage high runtime complexity. Ignoring features may increase classification errors.
Lal Shankar, Kulkarni Parag, Singh Amarjit   +2 more
doaj   +1 more source

Multiscale nature of network traffic [PDF]

IEEE Signal Processing Magazine, 2002
The complexity and richness of telecommunications traffic is such that one may despair to find any regularity or explanatory principles. Nonetheless, the discovery of scaling behavior in teletraffic has provided hope that parsimonious models can be found.
Patrice Abry, Richard G. Baraniuk, Patrick Flandrin, Rudolf H. Riedi, Darryl Veitch   +4 more
openaire   +3 more sources

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Using Generalized Entropies and OC-SVM with Mahalanobis Kernel for Detection and Classification of Anomalies in Network Traffic

Entropy, 2015
Network anomaly detection and classification is an important open issue in network security. Several approaches and systems based on different mathematical tools have been studied and developed, among them, the Anomaly-Network Intrusion Detection System (
Jayro Santiago-Paz, Deni Torres-Roman, Angel Figueroa-Ypiña, Jesus Argaez-Xool   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A deep learning‐based framework to identify and characterise heterogeneous secure network traffic

IET Information Security, 2023
The evergrowing diversity of encrypted and anonymous network traffic makes network management more formidable to manage the network traffic. An intelligent system is essential to analyse and identify network traffic accurately.
Faiz Ul Islam, Guangjie Liu, Weiwei Liu, Qazi Mazhar ul Haq   +3 more
doaj   +1 more source