Results 101 to 110 of about 271,920 (286)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Intelligent Question Answering in Restricted Domains Using Deep Learning and Question Pair Matching
IEEE Access, 2020 With the rapid expansion of the Internet, intelligent question answering for information retrieval has once again gained widespread attention. However, current question answering models mainly focus on the general and common-sense questions in open ...
Lin-Qin Cai +3 more
doaj +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
A Novel Fault Early Warning Model Based on Fault Gene Table for Smart Distribution Grids
Energies, 2017 Since a smart distribution grid has a diversity of components and complicated topology; it is very hard to achieve fault early warning for each part. A fault early warning model for smart distribution grid combining a back propagation (BP) neural network
Min Xiang +3 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Friction, 2019 Magnetorheological elastomer (MRE) is a type of smart material of which mechanical and electrical properties can be reversibly controlled by the magnetic field.
Rui Li +4 more
doaj +1 more source
Controlling Networks of Imitative Agents
IEEE Transactions on Network Science and Engineering, 2017 We consider how asynchronous networks of agents who imitate their highest-earning neighbors can be efficiently driven towards a desired strategy by offering payoff incentives, either uniformly or targeted to individuals. In particular, if for each available strategy, agents playing that strategy receive maximum payoff when their neighbors play that ...
James R. Riehl +2 more
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source