Results 81 to 90 of about 17,888,976 (294)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Separation principle for networked control systems with multiple-packet transmission

, 2011
The authors investigate a class of observer-based discrete-time networked control systems (NCSs) with multiple-packet transmission where random packet dropouts occur independently in both the sensor-to-controller (S/C) and controller-to-actuator (C/A ...
Wu, Jun, Chen, Sheng, Wu, Dongxiao
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Approximate Dynamic Inversion for Nonaffine Nonlinear Systems With High-Order Mismatched Disturbances and Actuator Saturation

IEEE Access, 2020
In this paper, a novel disturbance-observer-based approximate dynamic inversion (ADI) approach is developed for pure-feedback nonaffine-in-control nonlinear systems (PFNNSs) in the presence of both high-order mismatched disturbances and actuator ...
Hao Yang, Hailong Pei
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Novel Approach to ECG Classification Based upon Two-Layered HMMs in Body Sensor Networks

Sensors, 2014
This paper presents a novel approach to ECG signal filtering and classification. Unlike the traditional techniques which aim at collecting and processing the ECG signals with the patient being still, lying in bed in hospitals, our proposed algorithm is ...
Wei Liang, Yinlong Zhang, Jindong Tan, Yang Li   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Stability of networked control systems based on switched technique

, 2003
In this paper we discuss the stability of networked control systems where the networked-induced delay tau(k) is not constant. We introduce some novel concepts and design feedback matrices K-i and a switched strategy among them.
Yu HB(于海斌), Liu YZ(刘玉忠)
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

On Energy-Aware Communication and Control Co-design in Wireless Networked Control Systems [PDF]

, 2010
International audienceEnergy is a key resource in Networked Control Systems, in particular in applications concerning wireless networks. This paper reviews the multi-layer architecture of those systems in the light of their energy-use, and points out ...
Cardoso de Castro, Nicolas, De Wit, C. C., Karl Henrik Johansson, Canudas de Wit, Carlos, Johansson, Karl Henrik,, Johansson, Karl Henrik, Nicolas Cardoso de Castro, Carlos Canudas de Wit, De Castro, N. C.   +8 more
core   +1 more source