Results 101 to 110 of about 1,139,490 (222)

Determinants of sorghum adoption and land allocation intensity in the smallholder sector of semi-arid Zimbabwe

Spanish Journal of Agricultural Research, 2019
Sorghum is important for sustainability of smallholder farmers’ subsistence, social and economic livelihoods in semi-arid and arid environments of Southern Africa.
Joseph P. Musara, Lovemore Musemwa, Munyaradzi Mutenje, Abbyssinia Mushunje, Charles Pfukwa   +4 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Percolation of hierarchical networks and networks of networks

Physical Review E, 2018
Much work has been devoted to studying percolation of networks and interdependent networks under varying levels of failures. Researchers have considered many different realistic network structures, but thus far no study has incorporated the hierarchical structure of many networks.
Shekhtman, Louis M., Havlin, Shlomo
openaire   +3 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Interaction and problems in the abaca industry in Region VIII, Philippines

Ho Chi Minh City Open University Journal of Science - Economics and Business Administration
This article aims to elucidate the level of interaction among the different players in the abaca business enterprise in Region VIII, Philippines. The study used a survey method that gathered primary data from farmers, Local Government Units (LGUs ...
Milagros C. Bales, Karen Luz P. Yap, Fatima T. Baliña, Leomarich F. Casinillo   +3 more
doaj   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Understanding Small Business Networking and ICTs: Exploring Face-to-Face and ICT-related opportunity creation mediated by Social Capital in East of England Micro-businesses [PDF]

, 2010
Small businesses that are sole traders or micro-businesses—with few, if any employees notoriously suffer from a ‘liability of smallness’ (Aldrich and Auster 1986), including poor access to various resources.
Ellis, Rebecca
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Marketing of Library Services and Products through Social Media: An Evaluation [PDF]

, 2013
Social media has a great impact on information promotional activities by bringing tremendous changes in the field of marketing. Social networking applications help the users to possess interconnections among the community members and remix the library ...
Gireesh Kumar, T. K., Muruli, N
core  

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source