Results 121 to 130 of about 392,800 (301)

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Networking Talent Day 2017 - Simon

, 2017
Material en brut de l'entrevista a Simon dins el Networking Talent Day ...

core  

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Communications and Networking

, 2010
This book "Communications and Networking" focuses on the issues at the lowest two layers of communications and networking and provides recent research results on some of these issues.

core   +1 more source

Being queer (in libraries) is political

Library Ideas
Queerbrarians is a German-speaking network of queer librarians and people working or aiming to work in libraries or library institutions that was founded in November 2023. Based upon topics gathered at the first network meeting, this article presents the
Claudia Frick, Philipp Zeuner, Caleb Buchert, Daniela Markus, Norma Fötsch, Yvonne Fischer, Emma Wieseler, Sabrina Ramünke, Nik Baumann   +8 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Networking Talent Day 2017 - Estudiant2

, 2017
Material en brut de l'entrevista a una alumna de l'ESEIAAT dins el Networking Talent Day ...

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Interview with Mario Garcia DurhamNew York Scene : Inside the Association of Performing Arts Presenters (APAP)

Miranda: Revue Pluridisciplinaire du Monde Anglophone, 2016
Interview with Mario Garcia Durham, director of the Association of Performing Art Presenters (APAP) in New York City. Conducted in July 2016 via Skype.
Margaux Szuter
doaj