Results 101 to 110 of about 392,800 (301)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Data protection: the challenges facing social networking [PDF]

open access: yes, 2010
The popularity of social networking sites has increased dramatically over the past decade. A recent report indicated that thirty-eight percent of online users have a social networking profile.
Garrie, DB   +7 more
core  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Software Defined Networking for CommunityNetwork Testbeds [PDF]

open access: yes, 2013
Wireless Community Networks have received increasing attention the latest years. In an effort to set the cornerstone for an internet without central authorities and monopolies, network engineers throughout the world have started creating community ...
Navarro, Leandro   +7 more
core   +1 more source

Back Matter - JTSiskom Volume 5 Nomor 1 Tahun 2017

open access: yesJurnal Teknologi dan Sistem Komputer, 2017
Artikel ini berisi back-matter JTSiskom Volume 5 Nomor 1 Tahun 2017, yaitu meliputi indeks penulis, petunjuk penulisan dan kirim artikel JTSiskom, perjanjian pengalihan hak cipta, form pengalihan hak cipta, pernyataan etika publikasi dan lisensi isi ...
Ketua Editor JTSiskom
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Networking for career success : dua puluh empat acuan untuk mengenali orang yang tepat

open access: yes, 2005
Judul Asli : Networking for career success107 p.
Darling, Diane
core  

Adolescent social networking: should parents and teachers be worried? [PDF]

open access: yes, 2011
Over the past few years, there has been a significant increase in the number of media stories about social networking. This has also led to a recent upsurge in the amount of empirical research being carried out.
Kuss, DJ, Griffiths, MD
core  

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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