Results 51 to 60 of about 392,800 (301)

Impact of Initial Treatment Setting on Survival in Relapsed Pediatric and AYA Bone Sarcomas: A Secondary Analysis of a Prospective Clinical Trial

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Outcomes in relapsed or refractory pediatric and AYA bone sarcomas remain poor, and the impact of early referral to specialized sarcoma centers on survival is unclear. Early centralization of care may improve local and systemic treatment quality, but evidence in this population is limited.
Justyna Antoniuk‐Majchrzak, Katarzyna Bilska, Tomasz Koziński, Jadwiga Węcławek‐Tompol, Dorota Sega‐Pondel, Radosław Chaber, Wanda Badowska, Katarzyna Rosłan, Hanna Koseła‐Paterczyk, Anna Raciborska   +9 more
wiley   +1 more source

Neurocognitive, School‐Based, and Quality of Life Outcomes for Youth With Sickle Cell Disease and Thalassemia: A Scoping Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT The medical burdens of sickle cell disease (SCD) and transfusion‐dependent β‐thalassemia (TDT) are chronic and cumulative, even in children. Yet the effects expand beyond medications and healthcare visits due to their impacts on school attendance, academic performance, and peer engagement.
Mary Ann Etling, Hakim Tokhi, Alexander A. Boucher   +2 more
wiley   +1 more source

Strengthening cybersecurity in a government department by addressing password management challenges and human factor vulnerabilities

Discover Computing
This study investigates password management challenges and human factor vulnerabilities within a South African district health department using a quantitative approach with 50 respondents.
Matipa Ricky Ngandu, Gardner Mwansa, Ziyanda Mkabe   +2 more
doaj   +1 more source

Uncovering Inequities: The Role of Social Determinants of Health in Hospitalized Adolescents and Young Adults With Heavy Menstrual Bleeding

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Heavy menstrual bleeding (HMB) is a common condition among adolescents and young adults (AYAs) and is the leading cause of iron deficiency anemia (IDA) in this population. Growing evidence suggests that social determinants of health (SDOH) influence menstrual bleeding patterns, access to care, and treatment. However, no studies have
Maria Carter‐Febres, Cristina Tarango, Ashley Childress, Chunyan Liu, Evan Thomas, Jennifer Pomales, Eric S. Mullins   +6 more
wiley   +1 more source

Operation of the Selected Local Action Group

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
The main objective of this article is to compare the current operation of elected local action group with the concept of learning regions. This comparison is built on detailed knowledge and understanding of the operation of local action group Podbrnensko
Lukáš Nevěděl, Miroslav Horák
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

From bench to bedside: Exploring the role of sCD25 in melanoma and lung cancer among sleep apnea patients

Pulmonology
Introduction and objectives The study examines how hypoxaemia in obstructive sleep apnoea (OSA) relates to cancer. It focuses on CD25, an immune-checkpoint, analyzing its levels in OSA patients with and without cancer to assess whether CD25 could serve ...
Elena Díaz-García, Enrique Alfaro, Paula Pérez-Moreno, Cristina López-Fernández, Aldara García-Sánchez, Miguel Ángel Martínez-García, Eva Mañas, Irene Cano-Pumarega, Raquel Casitas, Francisco Campos-Rodríguez, Manuel Sánchez-de-la-Torre, Eduardo Nagore, Antonio Martorell-Calatayud, Luis Hernández Blasco, Esther Pastor, Jorge Abad-Capa, Josep María Montserrat, Valentín Cabriada-Nuño, Jaime Corral-Peñafiel, Eva Arias, Olga Mediano, María Somoza-González, Joan Dalmau-Arias, Isaac Almendros, Fernanda Troncoso-Acevedo, Carolina Gotera-Rivera, Teresa Pérez-Warnisher, Germán Peces-Barba, Luis M. Seijo, David Gozal, Francisco García-Rio, Carolina Cubillos-Zapata   +31 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Towards interprofessional networking in medication management of the aged: current challenges and potential solutions in Finland

Scandinavian Journal of Primary Health Care, 2016
Objective: The Finnish Medicines Agency (Fimea) initiated a programme in 2012 for enhancing interprofessional networking in the medication management of the aged. The goal is to develop national guidelines for interprofessional collaboration with respect
Sonja Kallio, Anne Kumpusalo-Vauhkonen, Timo Järvensivu, Antti Mäntylä, Marika Pohjanoksa-Mäntylä, Marja Airaksinen   +5 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source