Results 71 to 80 of about 392,800 (301)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The role of organizational ties managed by practice firms. The case of Perting Ltd
Revista Internacional de Organizaciones, 2017 The paper analyzes the organizational ties created by the functional offices of Perting LtD, the Practice Firm established since 2001 in Bologna University, with teachers / tutors (educational ties), with other offices (operative-internal ties) and ...
Massimo Bianchi +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
A FOLK HIGH SCHOOL AS A FACTOR OF IMPROVING THE SOCIAL WELL-BEING OF A THIRD AGE PERSON
Russian Journal of Education and PsychologyBackground. The Strategy of Action for the Citizens of the Older Generation in the Russian Federation until 2025, which received high appraisal by the expert community when it was published in 2016, is close to summarizing its results.
Olga V. Gordina, Alexsandr I. Gordin
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Marketing technologies for building competitiveness of companies export [PDF]
International Economic Policy, 2017 In context of post-industrial development of global economy, escalating competition in international goods markets, the definition of competitive export is proposed based upon both existing criteria – sustainability, effectiveness, adaptivity and fair
Tatyana Tsygankova, Anna Ishchenko
doaj
Self management reflective practice in scotland
International Journal of Integrated Care, 2019 Self Management means ensuring people are in the driving seat of their health and wellbeing, recognising that everyone has strengths, skills and experience that support their health and wellbeing and enable them to manage the impact of their long term ...
Marianne Brennan
doaj +1 more source
Strategic model of production network, storage and optimization of distribution process [PDF]
مطالعات مدیریت راهبردی, 2021 Aim and introduction: The Ministry of Defense and Armed Forces Logistics is responsible for the planning, coordination, support, and expansion of the defense power; this ministry is responsible for equipping the defense forces to encounter the possible ...
Mahdi Moradi +3 more
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source