Results 151 to 160 of about 13,581,527 (336)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Equilibrium Fee Schedules in a Monopolist Call Market [PDF]
Liquidity plays a crucial role in financial exchange markets. Markets typically create liquidity through spatial consolidation with specialist/market makers matching orders arriving at different times. However, continuous trading systems have an inherent
Jeff Heisler, Nicholas Economides
core
, 2005 Inspired by Pythagoras's belief that numbers are the absolute reality, we obtain some demonstrational results about topological properties of integer networks, in which the vertices represent integers and two vertices are neighbors if and only if there ...
Albert +30 more
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Real Options and the Costs of the Local Telecommunications Network [PDF]
The Telecommunications Act of 1996 invites entry in the local telecommunications networks whereby entrants will lease parts of the network ("unbundled network elements") from incumbents "at cost plus reasonable profit." A crucial question in the ...
Nicholas Economides
core
Multi-fractal analysis of weighted networks [PDF]
, 2014 In many real complex networks, the fractal and self-similarity properties have been found. The fractal dimension is a useful method to describe fractal property of complex networks.
Chen, Xiaowu +5 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
地震科学进展In this paper, the regional full waveform inversion using the broadband waveforms recorded by China Seismic Network were conducted, and the focal mechanism solutions of the 62 earthquakes with M≥4.0 occurred in the mainland of China during November 2023 ...
Shanshan Liang +3 more
doaj +1 more source
The Quest for Appropriate Remedies in the Microsoft Antitrust EU Cases: A Comparative Appraisal [PDF]
The Microsoft cases in the United States and in Europe have been influential in determining the contours of the substantive liability standards for dominant firms in US antitrust law and in EC Competition law.
Ioannis Lianos, Nicholas Economides
core