Results 141 to 150 of about 13,581,527 (336)
Dizhen xuebao鲁东—黄海地块西部为华北地块东侧的次级地块，其地震活动具有显著的周期特征，地块内部的中强地震活动特征和周边大震对该地区的影响对研究该地区地震活动状态有重要意义。采用小波分析方法定量计算了鲁东—黄海地块西部历史地震的活动周期，并结合中强地震活动的定性分析、时空演化、能量释放及周边大震等资料，探讨了该地区的地震活动特征。结果显示：① 鲁东—黄海地块西部M5.0以上地震活动存在着60.6—78.6 a的长周期，该周期反映了地震活跃—平静的韵律特征，据此M≥5.0地震可划分为活跃时段 Ⅰ （1844—1879年）
Mingxiao Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
U.S. Telecommunications Today, April 1999 [PDF]
This short essay examines the current conditions in the US telecommunications sector (April 1999). We examine the impact of technological and regulatory change on market structure and business strategy.
Nicholas Economides
core
Networks, NetWorks, NETWorks, NETWORKS
, 1997 Business networks are having different characteristics and building blocs when looked upon from diverse perspectives. In this paper the aim is to highlight some aspects of the multi-facetted nature of business networks in marketing between industrial companies especially. A model is used as a base for discussing different networks in business settings.
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Economics of Network Neutrality [PDF]
Pricing of Internet access has been characterized by two properties. Parties are directly billed only by the Internet Service Provider (ISP) through which they connect to the Internet and the ISP charges them on the basis of the amount of information ...
Benjamin Hermalin, Nicholas Economides
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Intracellular Regulatory Networks are close to Monotone Systems [PDF]
, 2007 Several meso-scale biological intracellular regulatory networks that have specified directionality of interactions have been recently assembled from experimental literature.
Avi Ma' +2 more
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Seed selection for information cascade in multilayer networks
, 2017 Information spreading is an interesting field in the domain of online social media. In this work, we are investigating how well different seed selection strategies affect the spreading processes simulated using independent cascade model on eighteen ...
E Omodei +5 more
core +1 more source